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Headache clinical trials

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NCT ID: NCT04799015 Recruiting - Clinical trials for Post-Traumatic Headache

Dexamethasone for Post Traumatic Headache

Start date: February 24, 2021
Phase: Phase 4
Study type: Interventional

This is a randomized study of intravenous metoclopramide + intravenous dexamethasone versus intravenous metoclopramide for patients with acute post-traumatic headache.

NCT ID: NCT04765501 Recruiting - Headache Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Impact Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Impact Questionnaire (HIQ).

NCT ID: NCT04744129 Recruiting - Headache, Migraine Clinical Trials

Headache Inducing Effect of NN414 in Migraine Patients

Start date: February 25, 2022
Phase: N/A
Study type: Interventional

To investigate the role of KATP channels on the cerebral hemodynamic in migraine patients.

NCT ID: NCT04736654 Recruiting - Headache Clinical Trials

Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire

Start date: March 1, 2021
Phase:
Study type: Observational

The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).

NCT ID: NCT04726592 Recruiting - Migraine Clinical Trials

Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room

Start date: July 8, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of clorazepate in addition to the usual medication for treating migraine attack in the emergency room

NCT ID: NCT04715685 Recruiting - Migraine Clinical Trials

Mind Body Balance for Pediatric Migraine

Start date: March 9, 2021
Phase: N/A
Study type: Interventional

This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.

NCT ID: NCT04707586 Recruiting - Headache Clinical Trials

Lokal Cold Application in Nitroglycerin-Induced Headache (NIH)

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

The study was planned to evaluate the effect of local cold application on headache severity in individuals who received intravenous nitroglycerin treatment, which mostly causes headache due to its vasoditator effect. It is thought that the results to be obtained may provide evidence for the development of patient care guidelines.

NCT ID: NCT04696458 Recruiting - Migraine Clinical Trials

Effects of a Multispecies Probiotic on Migraine

Start date: April 15, 2021
Phase: N/A
Study type: Interventional

The prevalence of migraine is higher in female patients with various intestinal diseases. An explanation could be that migraine is caused by a leaky gut, defined by increased intestinal permeability that permits particles to pass through the gastrointestinal wall. Probiotics, may be able to improve intestinal barrier function. OBJECTIVE: To test whether probiotics, as adjucnt therapy, can reduce incidence and severity of migraine attacks by reducing intestinal permeability.

NCT ID: NCT04688255 Recruiting - Clinical trials for Brain Injuries, Traumatic

Mobile Subthreshold Exercise Program for Concussion--R01

MSTEP-R01
Start date: March 22, 2021
Phase: N/A
Study type: Interventional

Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue for weeks or months. PPCS results in greater utilization of sub-specialty care and can impact immediate and long-term social development, cognitive function and academic success. Previous recommendations for treating PPCS have focused on cognitive and physical rest, but more recently guidelines have shifted based on new research suggesting the benefit of rehabilitative exercise for PPCS. The rationale behind using exercise to treat youth with concussion is that gradually increasing physical activity facilitates return to full function. Rehabilitative exercise has since become one of the most common approaches to treating youth with PPCS, but access is challenging since most programs require weekly centralized visits with a concussion specialist. To bridge this gap, the investigators developed a telehealth-delivered approach to treat PPCS, utilizing physical activity trackers (Fitbits) and weekly video conferences with trained research staff. They then conducted a series of pilot studies with this approach, finding excellent feasibility, acceptability, and evidence for more rapid declines in concussive symptoms compared to controls. The investigators also found preliminary evidence that mechanisms behind this intervention may stem from both physiologic processes due to increased moderate-to-vigorous physical activity (MVPA) and psychologic processes such as reducing fear- avoidance of concussive symptoms. They now propose a fully-powered randomized controlled trial (RCT) to asses the efficacy of the "Mobile Subthreshold Exercise Program" (M-STEP) for treating youth with PPCS.

NCT ID: NCT04685772 Recruiting - Headache Clinical Trials

Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches

Start date: April 1, 2021
Phase:
Study type: Observational [Patient Registry]

This novel pilot project will assess the effectiveness of corticosteroids in treatment of acute post-concussion headache. The investigators hypothesize that the use of corticosteroids will cause significant headache reduction in frequency and/or intensity than individuals who undergo the current standard of care. Additionally, the investigators hypothesize that corticosteroid use will lead to a reduction in other somatic symptoms including vestibular symptoms, leading to quicker return to school, work, and/or ability to play sports.