Headache, Migraine Clinical Trial
Official title:
Adrenomedullins Headache Inducing Effects on Migraine Without Patients
AM is a naturally occurring peptide in the body and consists of 52 amino acids. AM belongs to the calcitonin gene-related peptide (CGRP) superfamily and has several structural, physiological and pharmacological similarities to CGRP, intermdine and amylin. In a randomized double-blind, placebo controlled cross-over design 20 migraine patients without aura recruited to receive infusion of adrenomedullin or placebo (saline).
AM is a naturally occurring peptide in the body and consists of 52 amino acids. AM belongs to
the calcitonin gene-related peptide (CGRP) superfamily and has several structural,
physiological and pharmacological similarities to CGRP, intermdine and amylin. In a
randomized double-blind, placebo controlled cross-over design 20 migraine patients without
aura recruited to receive infusion of adrenomedullin or placebo (saline).
A pilot study on healthy volunteers were conducted to determine tolerable dose of
adrenomedullin to the main study.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05503082 -
Ubrogepant treatmeNt in mIgraine Patients Utilizing mOnoclonal aNtibodies
|
Phase 4 | |
| Completed |
NCT04905654 -
Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura
|
N/A | |
| Recruiting |
NCT04091789 -
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
|
Phase 2 | |
| Completed |
NCT03337620 -
Efficacy and Safety of Tx360® Transnasal Sphenopalatine Ganglion Block in the Treatment of Chronic Migraine
|
Phase 3 | |
| Completed |
NCT02259387 -
Adolescents With Migraine: What's Stress Got To Do With It?
|
||
| Completed |
NCT05658185 -
Migraine Difficult to Treat: the Importance of Psychological Care in the Chronic Patient
|
N/A | |
| Completed |
NCT05001399 -
Feasibility of Using Holographic Memory Resolution® (HMR) in Patients/Clients With Pain
|
N/A | |
| Completed |
NCT03490500 -
Using the S100B Protein for Emergency Headache Management Care (S100)
|
||
| Completed |
NCT03075020 -
Carbon Monoxide Migraine-inducing Effects in Patients With Migraine Without Aura.
|
N/A | |
| Recruiting |
NCT03472092 -
Mind and Body Approaches to Pain Reduction in Youth With Migraine
|
Phase 2 | |
| Enrolling by invitation |
NCT04976985 -
Osteopathic Manipulative Treatment and Migraine Headaches
|
N/A | |
| Active, not recruiting |
NCT04372264 -
Intravenous Paracetamol, Dexketoprofen and Ibuprofen in the Treatment of Acute Migraine Attack Headache
|
Phase 4 | |
| Recruiting |
NCT04623203 -
The Prognosis of Migraine and Tension-Type Headache in Children and Adolescents
|
||
| Completed |
NCT04577443 -
The Effect of Adenosine on Cranial Hemodynamic, Headache and Migraine Induction Properties.
|
N/A | |
| Completed |
NCT03560024 -
The Effect of PACAP27 on the Extra- and Intracerebral Arteries Assessed by Magnetic Resonance Angiography (MRA) on Healthy Volunteers
|
N/A | |
| Completed |
NCT03228355 -
Headache Inducing Effect of Cromakalim in Migraine Patients
|
N/A | |
| Completed |
NCT02438553 -
Short-term Effectiveness of Transcutaneous Nerve Stimulation in Reducing Migraine Related Pain
|
N/A | |
| Recruiting |
NCT03577548 -
Influence of Main Psychological and Social Factors on Primary Headaches
|
||
| Recruiting |
NCT04715685 -
Mind Body Balance for Pediatric Migraine
|
N/A | |
| Completed |
NCT05853900 -
Study of Two Digital Therapeutics for the Prevention of Episodic Migraine
|
Phase 3 |