Head Trauma Clinical Trial
Official title:
Effect of Cervical Collar on the Optic Nerve Sheath in Minor Head Trauma Patients
This is randomized, controlled and blinded study was performed in minor head trauma patients. Two sonographers measured optic nerve sheath diameters (ONSD) of each subjects' eyes separately for different time points. Then a mean ONSD was calculated for before c-collar placement (T0), 5 and 20 minutes in supine position.
Head trauma is an important cause of morbidity and mortality. Increased intracranial pressure (ICP) can lead to decreased cerebral perfusion and tissue damage. It is important to be able to detect increased ICP on time, so that treatment can be initiated to prevent further brain damage. The measurement of optic nerve sheath diameter (ONSD) has been proposed as a non-invasive and rapid way to assess elevated ICP (1-2). Traditional ICP monitoring methods such as external ventricular devices are invasive and time-consuming and can only be performed by trained personnel at trauma centers. The optic nerve is surrounded by a protective sheath and is found on the back of the globe. Easily evaluated with ultrasonics. This is typically done with a linear probe measuring the diameter of the optic nerve sheath 3 mm back from where the contrast is highest. The normal upper limit for adults is 5 mm, the values above are considered abnormal. Many studies have shown that an increased ONSD measured by bedside ultrasound correlates with increased IDC and in one study there is a correlation between ONSD> 5 mm and ICP> 20 cm H2O. Cervical spine (c-arms) and cervical vertebrae are often temporarily immobilized in patients with head trauma. It has been shown that placement of c-arms increases IBP. The decrease in venous outflow caused by c-arms in the forehead is an important mechanism for this increase in ICP. The increase in ICP occurs simultaneously with the application of c-arms in cadaver. It is thought that increased ONSD in trauma patients may be related to c-arms. If a c-collar application is found to increase ONSD, this trauma may make it difficult to use ONSD as an non-invasive estimate of ICP in patients. To the best of our knowledge, there is a study in healthy individuals investigating the possible effect of c-collar administration on ONSD. However, there is no comparative study of patients with head trauma. The investigators tried to measure ONSD before and after placement of cervical limbs in cases with minor head trauma. The aim of our study is to identify changes in the optic nerve sheath measurement after placement of the c-arms, and to determine whether these changes are due to the time immobilized by the c-arms. This is randomized, controlled and blinded study was performed in minor head trauma patients. Two sonographers measured optic nerve sheath diameters (ONSD) of each subjects' eyes separately for different time points. Then a mean ONSD was calculated for before c-collar placement (T0), 5 and 20 minutes in supine position. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03291964 -
Rapid MRI for Acute Pediatric Head Trauma
|
||
Completed |
NCT02828306 -
Computer Based Algorithm for Patient Specific Implants for Cranioplasty in Patients With Skull Defects
|
||
Completed |
NCT04505293 -
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
|
N/A | |
Not yet recruiting |
NCT02232347 -
Ketamine and Glutamate After Brain Injury : a Microdialysis Study
|
Phase 2 | |
Completed |
NCT01448473 -
Is a Two-Film Skull X-ray Series as Sensitive as a Four-Film Series in the Diagnosis of Skull Fractures in Paediatric Patients
|
N/A | |
Terminated |
NCT00847977 -
Interest of Using Balanced Fluid for Infusion at the Early Phase of an Acute Cranial Trauma for Limiting Hyperchloremic Acidosis
|
Phase 3 | |
Completed |
NCT00622778 -
Immunemodulation in Patients With Minor Head Injury
|
N/A | |
Completed |
NCT04495634 -
Evaluation of a Carbon Nanotube Enabled Solid-State Head CT
|
N/A | |
Terminated |
NCT03680911 -
NAC for Head Trauma-induced Anosmia
|
Phase 3 | |
Recruiting |
NCT06173427 -
Monitoring of Intracranial Hemorrhage in Non-severe Head Trauma Patients Hospitalized in the UHCD
|
||
Terminated |
NCT06246500 -
Severe Head Trauma: Coagulation and CT-Scan Aggravation.
|
||
Withdrawn |
NCT03453749 -
Anti-secretory Factor as a Treatment for Adults With Severe Traumatic Head Injury
|
Phase 2 | |
Completed |
NCT00995683 -
Preventive Sodium Lactate and Traumatic Brain Injury
|
Phase 2/Phase 3 | |
Not yet recruiting |
NCT05195606 -
The Effect of Auditory and Tactile Stimuli in Traumatic Coma
|
N/A | |
Completed |
NCT04020874 -
Reducing Head Impact Exposure in Hawaii High School Football
|
N/A | |
Not yet recruiting |
NCT06113939 -
Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning
|
N/A | |
Recruiting |
NCT05386966 -
Medicolegal Aspects of Head Trauma
|
||
Not yet recruiting |
NCT03704272 -
Supervisory Neglect, Non-Accidental Trauma, Brief Intervention, and Treatment Referral
|
N/A | |
Active, not recruiting |
NCT00196131 -
Problems With Morphine Use in Patients With a Severe Brain Injury
|
Phase 1/Phase 2 | |
Withdrawn |
NCT02798601 -
Early Induced Hypernatremia for the Prevention and Management of Brain Edema
|
N/A |