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NCT03582267 Clinical Trial

The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players

Head Trauma Clinical Trial

Official title:
The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03582267
Other study ID # 1706-066-1706
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 1, 2017
Est. completion date August 1, 2019

Study information
Verified date September 2019
Source Texas Christian University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Nutrition interventions may present a safe and relatively risk free intervention for protection against subconcussive impacts. Docosahexaenoic acid (DHA, 22:6n-3) is the principal Omega 3 polyunsaturated fatty acid in the brain, playing an integral role in the brain's development and structural integrity. The goal of this study is to determine if supplementation with DHA attenuates blood biomarkers of repetitive head trauma linked to sub-concussive impacts sustained in rugby participation.

Recruitment information / eligibility
Status Completed
Enrollment 50
Est. completion date August 1, 2019
Est. primary completion date August 1, 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Canadian national rugby athletes on 7s and 15s teams

Exclusion Criteria:

- None

Study Design

Related Conditions & MeSH terms

Intervention

Dietary Supplement:
• Docosahexaenoic Acid (DHA)
Daily administration of docosahexaenoic Acid (DHA). 2 grams of DHA liquid concentrate administered per day throughout trial period.

Locations
Country Name City State
United States Texas Christian Universti Fort Worth Texas

Sponsors (1)
Lead Sponsor Collaborator
Texas Christian University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Blood concentration of neurofilament light protein Concentrations of neuronally derived proteins measured in blood 12 times throughout course of 1 year
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