Clinical Trials Logo

Clinical Trial Summary

The objective of this study is to evaluate the impact of a clinical decision support (CDS) alert to facilitate the co-prescribing of naloxone, an opioid overdose reversal agent, with high-risk opioid prescriptions. Prescribing naloxone with opioids is a best practice described in the 2022 US Center for Disease Control and Prevention (CDC) guidelines on opioid prescribing. The CDS can improve quality of care delivered by improving compliance with the guideline defined best practices. The project will compare CDS alert facilitated co-prescribing of naloxone with high-risk opioid prescriptions vs usual care to evaluate the effectiveness of the CDS alert for improving naloxone prescribing. The patients are not assigned to an intervention and will be receiving any changes in care as part of their routine medical care, rather than a specific intervention that is distinct from their usual medical care. The researchers hypothesize that the CDS alert will be acceptable to providers while increasing naloxone co-prescribing which will reduce the number of opioid overdoses in subsequent 6 months.


Clinical Trial Description

Clinical decision support tools help clinicians make treatment decisions based on routinely collected data and offer a promising strategy to implement evidence-based practices for safe and effective pain management. This project will use clinical decision support tools embedded into electronic health records to help healthcare providers make treatment decisions that align with opioid prescribing guidelines from the Centers for Disease Control and Prevention (CDC). The project will also use information from prescription drug monitoring programs, insurance claims, and mortality data to evaluate patient outcomes. This research will evaluate how prescribing practices that align with CDC guidelines affect patient outcomes and whether clinical decision support tools provide an advantage over standard care practices for pain management. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06271668
Study type Observational
Source University of Colorado, Denver
Contact Heather Tolle, PhD
Phone 303-724-9924
Email heather.tolle@cuanschutz.edu
Status Not yet recruiting
Phase
Start date April 2024
Completion date September 2026

See also
  Status Clinical Trial Phase
Recruiting NCT05463341 - Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties N/A
Recruiting NCT02425657 - Fast Track Module Based Colonoscopy Training Programme for Surgical Trainees at North Jutland Surgical Departments
Completed NCT04253158 - Implementation of a Web-based Alcohol and Other Drug Prevention Intervention for Collegiate Student-athletes N/A
Active, not recruiting NCT04700930 - CBD Cigarettes Instead of Normal Cigarettes as Innovative Treatment for Schizophrenia N/A
Recruiting NCT05994703 - Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine Phase 2
Completed NCT04210180 - Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction Phase 2/Phase 3
Recruiting NCT06115746 - A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students N/A
Recruiting NCT05493475 - Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants N/A
Terminated NCT03675503 - Reducing Hospital Falls by Empowering Nurses to Provide Ambulatory Aids N/A
Completed NCT01838473 - In-vivo Extraction of Lead, Cadmium and Tobacco Specific Nitrosamines From Swedish 'Snus' in Regular Snus Users Phase 1
Completed NCT01369693 - In-vivo Extraction of Pb, Cd and TSNA From Swedish Snus Phase 1
Completed NCT01249339 - In-vivo Extraction of Pb, Cd andTSNA From Swedish Snus Phase 1
Completed NCT04250727 - Switching to Potential Reduced Exposure Products in Adult Smokers N/A
Completed NCT04650269 - Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program Phase 4
Completed NCT04268173 - Community-Based, Client-Centered Prevention Homes to Address the Rural Opioid Epidemic- Aim 3 Phase 3
Not yet recruiting NCT04351958 - An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens N/A
Active, not recruiting NCT05404815 - Exposure to Plasticisers in the Neonatal Intensive Care Unit
Not yet recruiting NCT06429436 - Vending Machine Naloxone Distribution for Your Community (VENDY) Phase 4
Not yet recruiting NCT06372899 - Alternative Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers N/A
Recruiting NCT05516069 - Our Healthbox - Evaluating Interactive Dispensing Systems for Low-Barrier Access to HIV Testing and Harm Reduction. N/A