Harm Reduction Clinical Trial
Official title:
Harm Reduction Strategies for Gay, Bisexual and Other Men Who Have Sex With Men Engaging in Chemsex
This study is examining the usability and effectiveness of an innovative mobile app that integrates harm reduction strategies into the existing pre-exposure prophylaxis (PrEP) intake and adherence app, with an overarching goal to reduce the potentially negative consequences of problematics chemsex behavior for individuals and communities.
The practice of sexualized drug use is historical and has been noted across a diversity of genders and people of various sexual orientations. The term "chemsex" has been used to specifically describe the use of psychoactive substances in sexualized settings among gay, bisexual, and other men who have sex with men (GBMSM), particularly stimulants like methamphetamine and mephedrone, or other drugs like γ-hydroxybutyrate (GHB), γ-butyrolactone (GBL). Chemsex among GBMSM has coincided with the emergence of sexual-networking mobile apps, creating new opportunities for finding new partners with the intention to engage in chemsex. Harm reduction strategies for GBMSM engaging in chemsex are needed because the use of these drugs can have negative consequences for the physical and mental health of the people who use them. One of the main risks associated with chemsex is the possibility of overdose. In addition to the risk of overdose, chemsex may also increase the risk of sexually transmitted infections (STIs) and HIV transmission due to the higher possibility to engage in risky sexual behaviors. Seeking help can be difficult for GBMSM who engage in chemsex due to stigma, making the harm reduction approach equally important as clinical treatment or intervention that emphasized an abstinence approach. Harm reduction strategies recognize that drug use is a complex issue and that it is not always possible or desirable for people to stop using drugs completely. Instead, harm reduction approaches aim to reduce the harm that can result from drug use and to support people in making healthier choices. Considering also that mobile applications are another way to provide help to hard to reach population, this study aims to develop an innovative mobile app that integrates harm reduction strategies into the existing pre-exposure prophylaxis (PrEP) intake and adherence app. PrEP is a medication that can be taken daily to reduce the risk of HIV transmission. The aim of including PrEP adherence in the self-help harm reduction strategy is to ensure that participants have access to and are using an effective HIV prevention method. Behavior regulation strategies such as providing education about the risks of drug use, overdose prevention and management, and HIV prevention through correct PrEP intake, can be integrated into a mobile app that aims to minimize the negative consequences of drug use and reduce the risks associated with it, with an overarching goal to reduce the potentially negative consequences of problematics chemsex behavior for individuals and communities. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05463341 -
Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties
|
N/A | |
| Recruiting |
NCT02425657 -
Fast Track Module Based Colonoscopy Training Programme for Surgical Trainees at North Jutland Surgical Departments
|
||
| Completed |
NCT04253158 -
Implementation of a Web-based Alcohol and Other Drug Prevention Intervention for Collegiate Student-athletes
|
N/A | |
| Active, not recruiting |
NCT04700930 -
CBD Cigarettes Instead of Normal Cigarettes as Innovative Treatment for Schizophrenia
|
N/A | |
| Recruiting |
NCT05994703 -
Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine
|
Phase 2 | |
| Completed |
NCT04210180 -
Combination of E-cigarettes and Varenicline for Tobacco Harm Reduction
|
Phase 2/Phase 3 | |
| Recruiting |
NCT06115746 -
A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
|
N/A | |
| Recruiting |
NCT05493475 -
Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants
|
N/A | |
| Terminated |
NCT03675503 -
Reducing Hospital Falls by Empowering Nurses to Provide Ambulatory Aids
|
N/A | |
| Completed |
NCT01838473 -
In-vivo Extraction of Lead, Cadmium and Tobacco Specific Nitrosamines From Swedish 'Snus' in Regular Snus Users
|
Phase 1 | |
| Completed |
NCT01369693 -
In-vivo Extraction of Pb, Cd and TSNA From Swedish Snus
|
Phase 1 | |
| Completed |
NCT01249339 -
In-vivo Extraction of Pb, Cd andTSNA From Swedish Snus
|
Phase 1 | |
| Completed |
NCT04250727 -
Switching to Potential Reduced Exposure Products in Adult Smokers
|
N/A | |
| Completed |
NCT04650269 -
Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program
|
Phase 4 | |
| Completed |
NCT04268173 -
Community-Based, Client-Centered Prevention Homes to Address the Rural Opioid Epidemic- Aim 3
|
Phase 3 | |
| Not yet recruiting |
NCT04351958 -
An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens
|
N/A | |
| Active, not recruiting |
NCT05404815 -
Exposure to Plasticisers in the Neonatal Intensive Care Unit
|
||
| Not yet recruiting |
NCT06429436 -
Vending Machine Naloxone Distribution for Your Community (VENDY)
|
Phase 4 | |
| Not yet recruiting |
NCT06372899 -
Alternative Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
|
N/A | |
| Recruiting |
NCT05516069 -
Our Healthbox - Evaluating Interactive Dispensing Systems for Low-Barrier Access to HIV Testing and Harm Reduction.
|
N/A |