View clinical trials related to Harm Reduction.
Filter by:In an open label, randomized, two-way cross-over study, 32 male healthy regular snus users will be given repeated doses of four different types of portion snus: "General", "Catch", "Catch Mini" and "Catch Dry Mini". Each portion of used snus will be collected and frozen (-20 oC) pending analysis of lead (Pb), cadmium (Cd), nicotine and tobacco specific nitrosamines (TSNAs). Unused snus is collected and deep frozen for analysis and calculation of extracted dose. Calculations of extracted amount of lead, cadmium, nicotine and tobacco specific nitrosamines (TSNAs) respectively, will be done for each type of snus.
Incarcerated adolescents engage in suicide ideation, self-harming behaviors and have poor coping abilities, suggesting a need for mental health intervention and treatment. Previous research on self-harm among community adolescents revealed that self-harmers were more likely than non-self-harmers to report suicidal ideation, and having made a suicide plan. This study plans to evaluate the suicidal intent of self-harming and non-self harming adolescent admitted at juvenile detention house in Taiwan. Furthermore, this study also plans to identify the prevalence and types of self-harming activities of incarcerated youths. Another purpose is to investigate the coping abilities of incarcerated youth, with evaluation of efficacy of short problem-solving skills therapy intervention by trained psychologists of three sessions for adolescents with poor coping adjustment; referral to adolescent psychiatrist when severe mental disorder or poor coping abilities were found. By analyzing their suicidal ideation, self-harming behaviors, and coping adjustment, the investigators will be able to give timely intervention and identify effective means and methods for better serving this population. This study hopes to help the incarcerated youth to replace their self-destructive behaviors with effective coping adjustment abilities.