Infusion of Depleted T Cells Following Unrelated Donor Stem Cell Transplant (ICAT) — ICAT

Haematological Malignancies Clinical Trial

Official title:
Adoptive Immunotherapy With CD25/71 Allodepleted Donor T Cells to Improve Immunity After Unrelated Donor Stem Cell Transplant

Status Completed

Clinical Trial Summary

The purpose of this study is to evaluate whether the administration of allodepleted donor T cells to patients with haematological malignancies after stem cell transplant can improve the recovery of the patients immune system.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01827579
Study type	Interventional
Source	University College, London
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	July 2014
Completion date	January 2020

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT01719341` - Study of Non-Myeloablative Haplo-identical Haematopoietic Stem Cell Transplantation in Patients With Haematological Malignancies or Acquired Aplastic Anaemia	N/A
Terminated	`NCT04865419` - Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies	Phase 1
Suspended	`NCT02988258` - Study of Adoptive Immunotherapy With Donor-derived CMV-specific T Cells for Recipients of Allo-HSCT	Phase 1
Completed	`NCT05148806` - Mass Evaluation of Lateral Flow Immunoassays for the Detection of SARS-CoV-2 (Covid-19) Antibodies
Terminated	`NCT01080664` - A Phase I, Dose-escalation Study of AS703569 Given Orally to Subjects With Haematological Malignancies	Phase 1
Withdrawn	`NCT01336478` - CD56+CD3- NK Cells Following Allogeneic Stem Cell Transplantation	Phase 1