Oral Helicobacter Pylori Eradication

Status Recruiting

Clinical Trial Summary

Helicobacter pylori (H. pylori) is a serious health threat that infects approximately half of the global population. In addition to colonizing the stomach, H. pylori has been shown to survive in the oral microenvironment and is associated with a variety of oral diseases, gastric eradication failure, and reinfection. Currently, traditional systemic antibiotic therapy has little effect on oral H. pylori, and mouthwashes available on the market for oral H. pylori eradication often contain multiple antibiotics or complex essential ingredients, which can cause unpredictable effects on the human body. Therefore, there is an urgent need for a mouthwash that does not contain antibiotics and is effective against oral H. pylori. This study focuses on the eradication effect of MAXPOWER Biological Antibacterial mouthwash on oral H. pylori in a population.

Clinical Trial Description

Inclusion criteria: oral H. pylori-positive patients, verified by H. pylori saliva test (HPS),aged 18-70 years visiting the outpatient clinic of Changhai Hospital from March 1, 2023, to August 1, 2023, were enrolled. Exclusion criteria: (1) Zollinger-Ellison syndrome, gastric cancer, upper gastrointestinal bleeding, or active peptic ulcer; (2) the coexistence of significant concomitant illnesses, including heart diseases, renal failure, hepatic disease, previous abdominal surgery, lactation or pregnancy; and (3) not willing to participate in the study. Written informed consent was obtained from all patients prior to participation in the study. ;

Study Design

Related Conditions & MeSH terms

H. Pylori Infection

Clinical Trial Details

NCT number	NCT06045832
Study type	Interventional
Source	Changhai Hospital
Contact	Yongkang Lai, Dr.
Phone	+86-18270881495
Email	4090275844@qq.com
Status	Recruiting
Phase	N/A
Start date	March 1, 2023
Completion date	September 30, 2023

View Details

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