Study of Biomarkers in Gynecological Cancers

Status Recruiting

Clinical Trial Summary

In recent years, there has been a significant improvement in understanding the biology of cancer and this information has been used to improve cancer care and patient outcome. Research has shown that changes in some genes and/or proteins may be important indicators for certain cancers and response to treatments. Genes are molecules made up of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). DNA contain instructions for the development and functioning of the cells in the body and are passed down from parent to child. RNA is involved with producing proteins in the body. Further research is needed to better understand the changes found in cancer cells and how to target them to stop or reduce cancer growth. A drug that may be able to block certain specific cancer cell changes is called "targeted therapy". Different people with the same type of cancer receiving the same drug could have different responses to it. For example, one person may experience a reduction of their tumor while another person's cancer may worsen. The reason for this is still not well understood and could lie in gene changes. Understanding these changes may allow researchers to predict how treatments may work in guiding decisions around choice of drugs. The purpose of the study is to learn more about gene changes or protein expression (levels) of tumors to better understand the behavior of gynecological diseases and, if possible, better address participants' cancer care now or in the future.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Gynecologic Cancer

Clinical Trial Details

NCT number	NCT03420118
Study type	Interventional
Source	University Health Network, Toronto
Contact	Amit Oza, M.D.
Phone	416-946-2818
Email	amit.oza@uhn.ca
Status	Recruiting
Phase	N/A
Start date	December 21, 2017
Completion date	December 21, 2025

View Details

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