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NCT03194347 Clinical Trial

Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

Gynecologic Cancer Clinical Trial

— MAGynMA  

Official title:
Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03194347
Other study ID # MAGynMA
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date May 29, 2017
Est. completion date May 31, 2021

Study information
Verified date February 2020
Source University Women's Hospital Tübingen
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the knowledge of a molecular-genetic finding affects the therapeutic decision of the physician. Furthermore, genetic changes in the tumor tissue will be compared with the changes in CTCs, DTCs and cfDNA.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 300
Est. completion date May 31, 2021
Est. primary completion date May 29, 2020
Accepts healthy volunteers No
Gender Female
Age group 18 Years and older
Eligibility Inclusion Criteria: - Patients with a solid tumor disease - The presence of a molecular genetic diagnosis of the tumor tissue from practice for human genetics - Age > 18 years - informed consent Exclusion Criteria: - life expectancy <12 months or worse general condition (Karnofsky <70)

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• molecular genetic analyses
molecular genetic analyses

Locations
Country Name City State
Germany University Women's Hospital Tübingen

Sponsors (1)
Lead Sponsor Collaborator
University Women's Hospital Tübingen

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Influence of molecular genetic findings to the therapy decision It will be analyzed if the physicians selection of a therapy is influenced by a present molecular genetic finding. Therapy recommondation based on molecular genetic analysis will be compared with the acutal therapy decision. 3years
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