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Observing the Relationship of Fibroblast Growth Factor and Fibroblast in Thyroid Eye Disease — TED  

Graves Ophthalmopathy Clinical Trial

Official title:
Observing the Relationship of Fibroblast Growth Factor and Fibroblast in Thyroid Eye Disease

Clinical Trial Summary

Graves' orbitopathy (GO) affects about 50% of patients with Graves' disease (GD), and some cannot be cured by current treatments. Orbital fibroblasts involves in the pathogenesis of GO by producing glycosaminoglycans and inflammatory cytokines. Since fibroblast growth factors (FGFs) binding to FGF receptors (FGFRs) can induce proliferation and differentiation of fibroblasts, investigators would like to measure the expression of FGFs and FGFRs in GO patients to see if inhibition of FGF-FGFR pathway has potential in treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03324022
Study type Observational
Source National Taiwan University Hospital
Contact Shyang-Rong Shih, M.D, Ph. D
Phone +886-2-23123456
Email srshih@ntu.edu.tw
Status Recruiting
Phase N/A
Start date December 25, 2014
Completion date December 25, 2020
View Details
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