Retinal Oxygen Saturation in Patients With Graves' Ophthalmopathy and in Normal People

Graves' Ophthalmopathy Clinical Trial

Official title: Changes of Retinal Oxygen Saturation in Patients With Graves' Ophthalmopathy Under Different Managing Conditions and in Normal People

Status Recruiting

Clinical Trial Summary

Find if the retinal function is affected in both the nonsevere and the severe stage of Graves' ophthalmopathy (GO) by comparing the retinal oxygen saturation of GO patients with that of normal people.

Clinical Trial Description

Graves'ophthalmopathy (GO), also called thyroid-associated ophthalmopathy, is often mild and self-limiting, and probably declining in frequency, with only 3-5% of cases posing a threat to eyesight, remaining a pathogenetic enigma and a therapeutic dilemma. In its nonsevere expression, the symptoms and signs include Photophobia, Foreign body sensation, Eyelid retraction, increased intraocular pressure, Lagophthalmos, and Mild diplopia. In its severe expression, it is a disfiguring and invalidating disease with the optic nerve damaged. However, in this study, we want to find if the retinal vessels is affected in the early stage of the disease through observing the oxygen saturation of the retinal vessels and compare it with that of the normal people. ;

Related Conditions & MeSH terms

• Eye Diseases
• Graves Ophthalmopathy
• Graves' Ophthalmopathy

• NCT number: NCT02290704
• Study type: Observational
• Source: Sun Yat-sen University
• Contact: Danping Huang
• Phone: +8613501508328
• Email: hdanp@mail.sysu.edu.cn
• Status: Recruiting
• Phase: N/A
• Start date: January 2014
• Completion date: November 2017