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Effects of Vitamin D Supplementation on Muscle Function Among Grave's Disease Patients

Graves Disease Clinical Trial

Official title:
Effects of Vitamin D Supplementation on Muscle Function Among Grave's Disease Patients

Clinical Trial Summary

Introduction: A deficit in vitamin D may be involved in the development and presentation of Graves' disease (GD). Lack of vitamin D and GD are linked to deteriorating quality of life (QoL) and weakening of the muscles. Our goal was to look at the possible advantages of vitamin D supplementation for the improvement of thyroid-related QoL and muscle function in GD patients, as well as the possible drawbacks of anti-thyroid drugs (ATD). Methodology: A multicenter randomized controlled experiment with single-blinding was carried out with 48 patients who had been diagnosed with Graves' illness. The participants were split into two groups n=24 patients in each group. In addition to standard ATD, Group A received either 70 μg (2800 IU) of vitamin D daily or a corresponding placebo. Investigator measured muscular function and isometric strength at baseline, three, and nine months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06451016
Study type Interventional
Source Frontier Medical and Dental College, Abbotabad
Contact
Status Completed
Phase N/A
Start date January 1, 2021
Completion date January 15, 2024
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