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NCT02231996 Clinical Trial

Chronic Granulomatous Disease Study in China

Granulomatous Disease, Chronic Clinical Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT02231996
Other study ID # CGD-20140829
Secondary ID
Status Not yet recruiting
Phase N/A
First received August 29, 2014
Last updated September 3, 2014
Start date September 2014

Study information
Verified date September 2014
Source Shanghai Children's Medical Center
Contact jing wu
Email wujingecnu@163.com
Is FDA regulated No
Health authority China: National Natural Science Foundation
Study type Observational [Patient Registry]

Clinical Trial Summary

CGD is a rare inherited primary immunodeficiency which is caused by the defect in one of the subunits of NADPH oxidase complex.We tend to collect and analyze Chinese CGD patients who are diagnosed in hospitals affiliated to Shanghai Jiao Tong University School of Medicine, including clinical feature, laboratory data and genetic information. we aim to find out clinical, distribution, genetic characteristic of CGD in Chinese population, etc., thus further improving the level of diagnosis and treatment for CGD.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 50
Est. completion date
Est. primary completion date August 2016
Accepts healthy volunteers No
Gender Both
Age group N/A to 18 Years
Eligibility Inclusion Criteria:

- x-linked and AR-linked Chronic Granulomatous Disease

- history of life-threatening severe infections

- A functional assay demonstrating abnormal NADPH oxidase function or clinical history consistent with CGD

Exclusion Criteria:

- Presence of other primary immunodeficiency syndromes that do not meet the clinical and laboratory criteria for CGD.

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
China Shanghai children's medical center Shanghai Shanghai

Sponsors (1)
Lead Sponsor Collaborator
Shanghai Children's Medical Center

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary times of pneumonia 2 years Yes
See also
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