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Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy using decidual stromal cell therapy for graft versus host disease after allogeneic hematopoietic stem cell transplantation. The hypothesis to be tested is that the cells are safe to infuse and that they have a positive clinical effect.


Clinical Trial Description

Patients with GVHD grade 2-4, will receive decidual stromal cells at approximately 1x10^6 cells/kg at one or more occasions at weekly intervals dependent on clinical response. ;


Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02172924
Study type Interventional
Source Karolinska Institutet
Contact Olle Ringdén, MD, PhD
Phone +46858582672
Email olle.ringden@ki.se
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date January 2017
Completion date December 2019

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