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A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host Disease

Graft vs Host Disease Clinical Trial

Official title:
A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host Disease

Clinical Trial Summary

The addition of rituximab to prednisone for the initial treatment of chronic GVHD will increase the overall response rate, enable a more rapid and effective steroid taper.

Clinical Trial Description

To determine the efficacy of Rituximab as first line of treatment of chronic GVHD. Efficacy will be defined as he ability to taper prednisone to a dose of 0.25 mg/kg per day by 6 months without clinical or GVHD relapse/ recurrence. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00350545
Study type Interventional
Source Stanford University
Contact
Status Completed
Phase N/A
Start date August 2006
Completion date October 2014
View Details
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