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A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

Gout Clinical Trial

Official title:
A Phase 1/2, Randomized, Double-blind, Placebo-controlled, Single Ascending and Multiple Dose Study of the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of ALN-XDH in Healthy Adult Subjects and Adult Patients With Gout

Clinical Trial Summary

The purpose of this study is to: - Part A: Evaluate the safety and tolerability of single ascending doses of ALN-XDH in healthy adult participants - Part B: Evaluate the safety, tolerability and efficacy of ALN-XDH as monotherapy in adult patients with gout - Part C: Evaluate the safety, tolerability and efficacy of ALN-XDH as add-on therapy in adult patients with gout

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05256810
Study type Interventional
Source Alnylam Pharmaceuticals
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date February 25, 2022
Completion date January 25, 2023
View Details
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