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Glomerulonephritis, Membranous clinical trials

View clinical trials related to Glomerulonephritis, Membranous.

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NCT ID: NCT05667909 Not yet recruiting - Clinical trials for Idiopathic Membranous Nephropathy

Prognostic Model of Rituximab in the Treatment of MN

Start date: June 2023
Phase:
Study type: Observational

The goal of this observational study is to explore the factors that can predict the prognosis difference in patients with idiopathic membranous nephropathy (IMN) under the treatment of rituximab. The main questions it aims to answer are: - to explore the factors that can predict the prognosis difference in patients with IMN under the treatment of rituximab - to establish a clinical prediction model and verify it to provide a reference for the early Participants will receive standard the treatment of rituximab treatment and will then be divided into remission and non remission groups based on the treatment effect after the standard treatment cycle. Blood, urine, and fecal samples were collected from patients to explore possible factors influencing treatment efficacy. Researchers will compare [remission group and non-remission group] to see if the gut microbiota and its metabolites are factors that influence the efficacy of treatment.

NCT ID: NCT05667896 Not yet recruiting - Clinical trials for Idiopathic Membranous Nephropathy

Prognostic Model of GC/TAC in the Treatment of MN

Start date: June 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to explore the factors that can predict the prognosis difference in patients with idiopathic membranous nephropathy (IMN) under the treatment of glucocorticoid + tacrolimus. The main questions it aims to answer are: - to explore the factors that can predict the prognosis difference in patients with IMN under the treatment of glucocorticoid + tacrolimus - to establish a clinical prediction model and verify it to provide a reference for the early Participants will receive standard the treatment of glucocorticoid + tacrolimus treatment and will then be divided into remission and non remission groups based on the treatment effect after the standard treatment cycle. Blood, urine, and fecal samples were collected from patients to explore possible factors influencing treatment efficacy. Researchers will compare [remission group and non-remission group] to see if the gut microbiota and its metabolites are factors that influence the efficacy of treatment.

NCT ID: NCT05667883 Not yet recruiting - Clinical trials for Idiopathic Membranous Nephropathy

Prognostic Model of GC/CTX in the Treatment of MN

Start date: June 2023
Phase:
Study type: Observational

The goal of this observational study is to explore the factors that can predict the prognosis difference in patients with idiopathic membranous nephropathy (IMN) under the treatment of glucocorticoid + cytoxan. The main questions it aims to answer are: - to explore the factors that can predict the prognosis difference in patients with IMN under the treatment of glucocorticoid + cytoxan - to establish a clinical prediction model and verify it to provide a reference for the early Participants will receive standard glucocorticoid + cytoxan treatment and will then be divided into remission and non remission groups based on the treatment effect after the standard treatment cycle. Blood, urine, and fecal samples were collected from patients to explore possible factors influencing treatment efficacy. Researchers will compare [remission group and non-remission group] to see if the gut microbiota and its metabolites are factors that influence the efficacy of treatment.

NCT ID: NCT05532111 Not yet recruiting - Efficacy and Safety Clinical Trials

Efficacy and Safety of the Treatment of Primary Membranous Nephropathy: A Randomized Clinical Trial

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

1. Main purpose: To evaluate the efficacy and safety of rituximab combined with tacrolimus in the treatment of intermediate and high-risk primary membranous nephropathy 2. Secondary research purposes: To describe the survival of patients with intermediate and high-risk primary membranous nephropathy treated with rituximab combined with tacrolimus; To describe renal survival in patients with intermediate and high-risk primary membranous nephropathy treated with rituximab combined with tacrolimus; 3. Exploratory research purposes: Feasibility of glucocorticoids-free therapy (rituximab combined with tacrolimus) in the treatment of intermediate and high-risk primary membranous nephropathy

NCT ID: NCT04498962 Not yet recruiting - Vascular Dementia Clinical Trials

The Effect of Danzhu Fuyuan Granule as Adjunctive Therapy for Chronic Stable Angina, Vascular Dementia and Idiopathic Membranous Nephropathy: A Bayesian Basket Trial

Start date: August 2020
Phase: N/A
Study type: Interventional

This study is designed as a bayesian basket trial , which aims to evaluate the efficacy of Danzhu Fuyuan Granule in patients with Chronic Stable Angina, Vascular Dementia and Idiopathic Membranous Nephropathy

NCT ID: NCT04326218 Not yet recruiting - Clinical trials for Membranous Nephropathy

Immunopathological Analysis in a French National Cohort of Membranous Nephropathy

IHMN
Start date: July 1, 2020
Phase: N/A
Study type: Interventional

National cohort of all cases of membranous nephropathy (MN) during a 1 year period in France, based on a pathological and/or serological diagnostic, collecting the data on: - incidence of MN - prevalence of anti-PLA2R1 and anti-THSD7A - clinical outcome one year after diagnosis or after relapse (complete remission, partial remission or persistent nephrotic syndrome) - environmental risk factors for the onset of MN - HLA markers - patient care status in France

NCT ID: NCT02610595 Not yet recruiting - Clinical trials for Idiopathic Membranous Nephropathy

Study on the Therapeutic Effect of TCM Treatment for MDR MN

Start date: December 2015
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of the Chinese medicine treatment for multiple drug resistance of MN patients with Jianpiyiqi and Huoxuejiedu Recipe.