Analyzing Pulsed Reduced Dose Radiotherapy in Upfront Glioblastoma

Status Recruiting

Clinical Trial Summary

The primary protocol objective is to assess the impact of substituting pulsed reduced dose radiotherapy (pRDR) for standard radiation therapy in the upfront treatment of glioblastoma (GBM) on disease progression.

Clinical Trial Description

This is a single-arm, single-center phase 2 study designed to assess the efficacy of pulsed reduced dose-rate radiotherapy in the initial treatment of maximally safely resected glioblastoma. The primary endpoint will be progression-free survival at six months. Patients with pathologically confirmed GBM who are planned for six weeks of adjuvant chemoradiation followed by six to12 months of adjuvant chemotherapy will be screened and enrolled after surgery. ;

Study Design

Related Conditions & MeSH terms

Glioblastoma

Clinical Trial Details

NCT number	NCT04747145
Study type	Interventional
Source	Medical College of Wisconsin
Contact	Medical College of Wisconsin Cancer Center Clinical Trials Offic
Phone	414-805-8900
Email	cccto@mcw.edu
Status	Recruiting
Phase	Phase 2
Start date	June 3, 2021
Completion date	June 2026

View Details

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