Glioblastoma Clinical Trial
Official title:
A Multicenter Phase II Study of 5-Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Newly Diagnosed or Recurrent Malignant Gliomas
The purpose of this study is to determine the safety and utility of 5-aminolevulinic acid
(ALA) for identifying your tumor during surgery. 5-ALA is not FDA approved at this time.
When the investigators remove the tumor from your brain, it is important that they remove
all of the tumor and not remove parts of normal brain. Sometimes this can be difficult
because the tumor can look like normal brain. In some brain tumors, 5-ALA can make the
tumors glow red under blue light. This may make it easier for your doctor to take out all of
the tumor from your brain. The purpose of this study is to:
- Make sure that 5-ALA helps the doctor remove more of the tumor.
- Make sure 5-ALA does not cause any side effects.
If you do not want to participate in this study, your doctor(s) will still do their best to
remove all of the tumor in your brain. Whether or not you join this study will not change
your treatment for your brain tumor.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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