A Trial Of PF-04856884 In Patients With Recurrent Glioblastoma

Status Withdrawn

Clinical Trial Summary

Angiopoietin-2 (Ang-2) is a protein in the body which destabilizes blood vessels and is important in stimulating tumor blood vessels. There is evidence suggesting that Ang-2 may be important for the growth and progression of Glioblastoma multiforme (GBM). PF- 04856884 (CVX-060) is a compound which binds Ang-2 and prevents its activity. The hypothesis is that PF-04856884 will be safe and effective in patients with recurrent Glioblastoma multiforme (GBM).

Clinical Trial Description

Notification of study being cancelled resulted in update in overall status change from "not yet recruiting" to "withdrawn." ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Glioblastoma

Clinical Trial Details

NCT number	NCT01225510
Study type	Interventional
Source	Pfizer
Contact
Status	Withdrawn
Phase	Phase 2
Start date	January 2011
Completion date	January 2013

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