Glioblastoma Clinical Trial
Official title:
Phase ll Trial of Tumor Lysate-Pulsed Dendritic Cell Immunotherapy for Patients With Atypical or Malignant, Primary or Metastatic Brain Tumors of the Central Nervous System
This research is being determine whether vaccinations with your own immune cells called " dendritic cells " can activate your immune system to fight your brain tumor.
To become eligible for therapy the following criteria must be fulfilled:
- No age or gender limit
- Patients with atypical malignant brain tumors.
- Must have a Karnofsky performance of at least 60%
- Hematologic studies and chemistry profiles will be within the parameters of the protocol
- Tumor specimen of adequate size to yield protein concentration, tumor lysate peptide
must be generated in sufficient quantity and patient must have no prior sensitivity to
the components of the dendritic cell vaccine.
- Patients are excluded if they have systemic disease, presence of acute infection, known
history of autoimmune disorder and pregnancy.
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|---|---|---|---|
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