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PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation

Glioblastoma Multiforme Clinical Trial

Official title:
PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation: A Randomized Phase II Study

Clinical Trial Summary

To obtain preliminary data in a randomized phase II study whether PPX/RT improves progression-free survival as compared to temozolomide/RT for patients with GBM without MGMT methylation.

Clinical Trial Description

To evaluate the toxicities of PPX/RT To evaluate neuro-cognitive functional assessments of patients with GBM receiving PPX/RT To obtain preliminary data in a randomized phase II study whether PPX/RT improves overall survival as compared to temozolomide /RT for patients with GBM without MGMT methylation to facilitate planning a phase III study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01402063
Study type Interventional
Source Brown University
Contact
Status Completed
Phase Phase 2
Start date September 2011
Completion date June 2015
View Details
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