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NCT03267849 Clinical Trial

Lamina Cribrosa Depth Change With Change in Eye Pressure

Glaucoma, Open-Angle Clinical Trial

Official title:
Lamina Cribrosa Depth Change With Change in Eye Pressure

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03267849
Other study ID # IRB00133667
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date July 1, 2017
Est. completion date July 1, 2025

Study information
Verified date July 2023
Source Johns Hopkins University
Contact Harry A Quigley, MD
Phone 4109552777
Email hquigley@jhmi.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This is a study of the compliance of the lamina cribrosa with change in eye pressure.

Description:

Glaucoma patients and control subjects will have their internal eye structure (lamina cribrosa) imaged by optical coherence tomography (OCT) standard images at two different eye pressures. In some participants, the eye pressure will be changed by one of two interventions, wearing goggles or having laser suturelysis

Recruitment information / eligibility
Status Recruiting
Enrollment 200
Est. completion date July 1, 2025
Est. primary completion date July 1, 2025
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 21 Years to 100 Years
Eligibility Inclusion Criteria: - persons who consent to drink water and be imaged Exclusion Criteria: - non-consenting persons - those who cannot be imaged

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• wearing swimming goggles or having laser suturelysis
Two images will be compared in each subject at two different eye pressures with the higher pressure having been produced by the interventions

Locations
Country Name City State
United States Johns Hopkins University Baltimore Maryland

Sponsors (1)
Lead Sponsor Collaborator
Johns Hopkins University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in anterior lamina cribrosa depth OCT position of lamina measured at 2 eye pressures. Data will be calculated as change in parameters of interest per mm Hg change in eye pressure Up to 2 months
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