Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic

Clinical Trial Description

This is a randomized trial comparing two elution doses of the Travoprost Intraocular implant to timolol ophthalmic solution in patients with open-angle glaucoma. Study assessments will include IOP and medication use as well as safety parameters. ;

Study Design

See also
Status	Clinical Trial	Phase
Recruiting	`NCT00306657` - Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition	N/A
Enrolling by invitation	`NCT04381611` - INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
Completed	`NCT06434155` - Social History and Glaucoma Progression

See also

Status

Clinical Trial

Phase

Recruiting

NCT00306657 - Normal Tension and Chronic Open Angle Glaucoma and Cerebrospinal Fluid Composition

N/A

Enrolling by invitation

NCT04381611 - INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register

Completed

NCT06434155 - Social History and Glaucoma Progression

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT02754596
Study type	Interventional
Source	Glaukos Corporation
Contact
Status	Completed
Phase	Phase 2
Start date	March 29, 2016
Completion date	July 21, 2020

Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms