Gingivitis Clinical Trial
Official title:
Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis and Gingivitis: a Randomised Controlled Clinical Trial
The purpose of this study is to analyze the efficacy of 0.12% chlorhexidine gluconate as a chemical adjuvant for the treatment of peri-implant mucositis in single implants compared with homologous teeth with gingivitis, in a non-surgical treatment protocol with a six-month follow-up.
The following clinical parameters were evaluated in both test and control groups; visible
plaque index (VPI) and gingival bleeding index (GBI) were obtained for full mouth (IPV and
ISG) and for each implant and teeth (VPI implant; VPI teeth; GBI implant; GBI teeth). For
statistical purposes, percentages of faces with biofilm and marginal bleeding at teeth and
implants were calculated. These parameters were evaluated at baseline and at one, three and
six months post-therapy.
Probing depth (PD implant; PD teeth) and bleeding on probing (BOP implant; BOP teeth) were
collected for all implants and teeth with a North Carolina periodontal probe at six sites.
After data collection, an arithmetic averages of the sites with bleeding on probing and
probing depths were calculated at baseline, three and six months. The peri-implant and
periodontal biotype for each implant and teeth was rated as thin or thick, according to
probe transparency during probing depth.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05568290 -
Interleukin-38 Levels in Individuals With Periodontitis
|
||
| Completed |
NCT04402996 -
Meteorin-like Levels in Individuals With Periodontitis
|
||
| Not yet recruiting |
NCT06016023 -
Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker
|
||
| Not yet recruiting |
NCT05497895 -
The Assessment of Clinical Efficacy of Topical Application of 5% Thymoquinone Gel for Gingivitis Patients
|
Early Phase 1 | |
| Completed |
NCT02884817 -
Essential Oil+ELA, Plaque and Gingivitis
|
Phase 4 | |
| Completed |
NCT02552589 -
Effect of Toothpaste on the Reduction of Plaque and Inflammation
|
N/A | |
| Completed |
NCT02633345 -
Effects on Tablets Containing Probiotic Candidate Strains
|
N/A | |
| Completed |
NCT02980497 -
Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study
|
N/A | |
| Completed |
NCT02515929 -
Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs
|
Phase 4 | |
| Unknown status |
NCT01956656 -
Efficacy Of Lotus Leaves In Management Of Plaque Induced Gingivitis
|
N/A | |
| Completed |
NCT02235532 -
Effects of Aloe Vera Toothpaste on Periodontal Parameters
|
N/A | |
| Completed |
NCT02508987 -
Obesity and Oxidative Stress in Patients With Different Periodontal Status
|
N/A | |
| Completed |
NCT01941797 -
Experimental Peri-implant Mucositis in Humans
|
N/A | |
| Completed |
NCT01593540 -
Clinical Examination of Metal Free Interdental Brushes
|
Phase 4 | |
| Unknown status |
NCT01197105 -
Evaluation Study of a Mouthwash Based on Schinus Terebinthifolius to Treat Gingivitis in Children
|
Phase 1/Phase 2 | |
| Completed |
NCT01236963 -
Essential Oils Mouth Rinse and Dental Floss: Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation
|
N/A | |
| Completed |
NCT02102295 -
Effects of Antioxidant Dentifrice on Gingivitis
|
Phase 3 | |
| Completed |
NCT06140784 -
A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices
|
N/A | |
| Completed |
NCT02937636 -
To Investigate the Gingivitis Efficacy of a Stannous Fluoride Dentifrice in a Chinese Population
|
N/A | |
| Completed |
NCT06212908 -
Assessment of Periodontal Therapy and Biofilm Management in Breast Cancer
|
N/A |