Garlic With Lime Juice and Chlorhexidine Mouthwash

Gingival Bleeding Clinical Trial

— mouthwash  

Official title:

Evaluation of Garlic With Lime Juice and Chlorhexidine Mouthwash on Gingival Bleeding in Group of Egyptian Children: A Randomized Clinical Trial

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT03105960
• Other study ID #: 151087
• Secondary ID: 151087
• Status: Enrolling by invitation
• Phase: N/A
• First received: March 21, 2017
• Last updated: April 4, 2017
• Start date: March 10, 2017
• Est. completion date: June 1, 2017

Study information

• Verified date: April 2017
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.

Description:

the study about herbal mouth wash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and show their effect on gingival bleeding and strepococcus bacteria present in saliva and plaque.

1. Preparation of garlic with lime juice will occur under aseptic condition.and give it to the first group.

provide chlorhexidine to the second group.

2. Collection of plaque and saliva samples will be obtained from children who fulfilled the inclusion criteria.

3. Asses gingival condition by asking patient.

4. Subjects will be instructed to rinse for 14 days, twice daily.

5. Morning after breakfast and night before going to bed.

6. With 10 ml (undiluted) of the assigned mouthwash for 30 s and then expectorate the rinse.

7. Again after 14 days, the saliva and plaque samples will be taken and inoculated on blood agar plates to determine the colony count and the gingival index by loe and illness will be assessed.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 36
• Est. completion date: June 1, 2017
• Est. primary completion date: June 1, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 9 Years to 12 Years

Eligibility

Inclusion criteria:

1. Children aged between 9 and 12 years.

2. Children are having normal occlusion (no crowding), non-compromised oral health (brushed their teeth once-daily) using toothbrush and non-fluoridated toothpaste. And practicing no other oral hygiene measures.

3. Medically free history.

4. Absence of orthodontic appliances.

Exclusion criteria:

1. History of current or recent (at least for the past 1 month) antibiotic usage or other medications.

2. Presence of Abscess, draining sinus, cellulitis, or other conditions requiring emergency dental treatment.

3. not willing to comply with the study.

Related Conditions & MeSH terms

• Gingival Bleeding
• Gingival Hemorrhage
• Hemorrhage

Intervention

Drug:
• garlic with lime mouth wash
garlic with lime juice is herbal antimicrobial 10 ml (undiluted) for 30s and then expectorate for 14 days.o prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.
• chlorhexidine
hlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days.

Locations

Country	Name	City	State
Egypt	Manal Sayed Abdel Latief	Helwan	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Tulsani SG, Chikkanarasaiah N, Siddaiah SB, Krishnamurthy NH. The effect of Propolis and Xylitol chewing gums on salivary Streptococcus mutans count: a clinical trial. Indian J Dent Res. 2014 Nov-Dec;25(6):737-41. doi: 10.4103/0970-9290.152182. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	gingival bleading	bleeding of gingiva asses by yes or no	15 day
Secondary	Streptococcal count in saliva and plaque	Streptococcal count in saliva and plaque	15 day

External Links

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