Mayo Clinic Tapestry 2.0: Applying Multi-Omics on Tapestry Participants for Scientific Discovery

Genetic Predisposition Clinical Trial

Official title:

Mayo Clinic Tapestry 2.0: Applying Multi-Omics on Tapestry Participants for Scientific Discovery

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06456320
• Other study ID #: 23-004120
• Status: Not yet recruiting
• Start date: August 26, 2024
• Est. completion date: December 31, 2027

Study information

• Verified date: June 2024
• Source: Mayo Clinic
• Contact: Blake Clermont
• Phone: 507-422-6373
• Email: tapestry2[@]mayo.edu
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to use multi-omics testing on samples collected from Mayo Clinic patients to build and expand on what has been learned about genomic data.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50000
• Est. completion date: December 31, 2027
• Est. primary completion date: December 31, 2027
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age = 18 years

• Registered Mayo Clinic patient

• Able to provide informed written consent

• Able to receive mail and packages within a United States (US) state

• Able to collect and ship samples within a US state

Exclusion Criteria:

• Active hematological cancer or history of a hematological cancer

• Allogeneic Bone Marrow Transplant (e.g., samples from autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)

• Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study (e.g., reduced ability to comprehend, i.e., dementia, intellectual disability, etc.)

Related Conditions & MeSH terms

• Genetic Predisposition
• Genetic Predisposition to Disease

Locations

Country	Name	City	State
United States	Mayo Clinic in Florida	Jacksonville	Florida
United States	Mayo Clinic in Rochester	Rochester	Minnesota
United States	Mayo Clinic in Arizona	Scottsdale	Arizona

Sponsors (1)

Lead Sponsor	Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Creation of a unique integrated asset of multi-omics data	A variety of patient cohorts will be ascertained throughout this study. Data will be made available to researchers to query correlations of disease states and clinical outcomes to multi-omics findings. These insights will be invaluable to creating omics-informed care plans in the future. Standard descriptive statistics approaches will be used for analysis.	Up to 5 years