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Generalized Anxiety Disorder clinical trials

View clinical trials related to Generalized Anxiety Disorder.

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NCT ID: NCT05380115 Withdrawn - Clinical trials for Generalized Anxiety Disorder

Cognitive Behavioral Therapy (CBT) for Late Life Anxiety

Start date: July 2024
Phase: N/A
Study type: Interventional

The purpose of this research study is to assess the acceptability and feasibility of the implementation strategy and fidelity of cognitive-behavioral therapy (CBT) for older adults with Generalized Anxiety Disorder.

NCT ID: NCT04965272 Withdrawn - Clinical trials for Generalized Anxiety Disorder

A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepressant Therapies (ADTs) Compared to Placebo in Adult Participants With Generalized Anxiety Disorder (GAD) Who Have Had an Inadequate Response to ADTs Alone

CAR aGAD Ph 2
Start date: August 18, 2021
Phase: Phase 2
Study type: Interventional

Generalized anxiety disorder (GAD) is usually treated with antidepressant therapy (ADT); however, sometimes ADTs alone are not enough to adequately treat GAD. The purpose of this study is to assess adverse events and the change in disease activity with cariprazine when added to ADTs compared with placebo in adult participants with GAD who have had an inadequate response to 1 or more prior ADTs alone. Cariprazine is an approved drug being developed for the treatment of GAD. The participants are placed into 1 of 4 groups, called treatment arms. Each group receives a different treatment. There is a 1 in 4 chance that participants will be assigned to placebo. Around 1072 participants age 18-65 with GAD and an inadequate response to ADT alone will be enrolled in the study in the United States. After a 2-week screening period, participants will receive daily oral capsules of cariprazine of varying doses or placebo for 6 weeks, followed by a 4-week safety follow-up period for a total study duration of 10 weeks. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.

NCT ID: NCT04569760 Withdrawn - Clinical trials for Generalized Anxiety Disorder

Cannabinoids for the Treatment of Anxiety Disorders: An 8-Week Pilot Study

Start date: April 2021
Phase: Phase 3
Study type: Interventional

This proposed study aims to evaluate the efficacy of a daily oral cannabinoid oil preparation in treating symptoms of DSM-5 anxiety disorders, using a two-arm, 8-week randomized, placebo-controlled trial in adults aged 21-65 years. The study will also evaluate the relationship between inflammation, anxiety and cannabinoids using biological markers as well as examine the neuro-cognitive effects of cannabinoid treatment.

NCT ID: NCT02382224 Withdrawn - Clinical trials for Generalized Anxiety Disorder

Worry Exposure for Generalized Anxiety Disorder

Start date: September 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the efficacy of a worry exposure intervention, a form of cognitive behavioral therapy (CBT), in comparison to a waitlist condition for the treatment of Generalized Anxiety Disorder. There will be a total of 60 subjects enrolled at the University of Texas at Austin. Patients will be randomized (like a flip of a coin) to either 12-sessions of WE therapy or a 12-week waitlist before being offered entry into therapy.

NCT ID: NCT00738738 Withdrawn - Clinical trials for Generalized Anxiety Disorder

6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD)

Start date: January 2009
Phase: Phase 3
Study type: Interventional

This is an open-label, multi-site, 6-month study of an investigational compound in elderly outpatients, age 65 years old or above, to assess the long-term safety and tolerability of the compound in the treatment of elderly subjects with Generalized Anxiety Disorder (GAD).