The Affecting Factors on Airway Temperature and Moisture

General Anesthesia Clinical Trial

Official title:

The Effects of Different Fresh Gas Flows and Different Anesthetics on Airway Temperature and Moisture in Patients Who Underwent General Anesthesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04204746
• Other study ID #: E.90598
• Status: Completed
• Start date: April 1, 2016
• Est. completion date: April 1, 2018

Study information

• Verified date: December 2019
• Source: Selcuk University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

There is no literature information about the flow rate of fresh gas mixture (air+O2) in the patients who underwent general anesthesia. Different flow rates of fresh gas mixture are used in both the investigator's hospital and the experiences of the anesthesiologists. It is aimed to study the effects of different fresh gas flow rates on the rate of temperature and moisture of the airway of patients who underwent general anesthesia.

Description:

Under physiological conditions, inhaled air is heated and humidified as it passes through the nose and upper airways until reaching the alveoli. This mechanism is bypassed by endotracheal intubation. Ventilation with dry and cold compressed gases leads to loss of water and heat from the respiratory tract. Drying of the respiratory tract can lead to destruction of the cilia and mucous membranes, resulting in decreased mucociliary transport and increased concentration of secretions.There is no definitive literature on fresh gas mix (oxygen + air) flow rates in patients under general anesthesia. This study aimed to investigate whether two fresh gas flow rates routinely employed in the authors' practice affected airway temperature and humidity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 240
• Est. completion date: April 1, 2018
• Est. primary completion date: April 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

Patients aged 18-65 years underwent general anesthesia -

Exclusion Criteria:admitted to emergency and trauma, history of advanced cardiac disease, cigarette use = 3 packet/day, pulmonary parenchymal disease such as malignancy or chronic obstructive pulmonary disease (COPD), history of thyroid disease, body mass index (BMI) greater than 30 kg/m2, alcohol and substance addiction, mentally deficiency, pregnancy or postpartum, fever and infection, drug use such that would influence thermoregulation such as vasodilators, hemorrhage > 5 mL/kg, and patients who declined to participate.

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Related Conditions & MeSH terms

• General Anesthesia

Intervention

Other:
• We will observe and evaluate the temperature and moisture in the respiratory circuit by a thermo-hygrometer.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Selcuk University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Affect of two fresh gas flow rates (3lt/ 6lt min) on patients' airway temperature and humidity.	We will evaluate if different fresh gas flows effect on patients' airway temperature and moisture. We will evaluate by using a thermo-hygrometer fixed on anesthesia circuit.	2016-2018
Secondary	Affect of different anesthetic gases (sevoflurane, desflurane) and drugs (propofol)on patients' airway temperature and humidity.	We will evaluate if different anesthetic gases (sevoflurane, desflurane) and drugs (propofol) effect on patients' airway temperature and moisture. We will evaluate by using a thermo-hygrometer fixed on anesthesia circuit.	2016-2018