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Clinical Trial Summary

During non urgent surgery, general anesthesia might induce enterocyte damage. I-FABP is a performant biomarker of enterocyte damage. We aimed to study whether patient ongoing general anesthesia for non-urgent surgery have an elevation of plasma I-FABP concentration.


Clinical Trial Description

Inclusion criteria

- Indication of non-urgent surgery

- General anesthesia protocol using propofol and remifentanyl

- One half of the patients have a history of ischemic arteriopathy

- One half of the patients have no history of ischemic arteriopathy

Exclusion criteria

- Age < 18 years old

- Pregnant

Primary objective

Is there a significant elevation of I-FABP between the pre-anesthesic period and 11 minutes after induction of general anesthesia ?

Secondary objectives

1. Is I-FABP elevation higher among patients with history of patent arteriopathy ?

2. Is I-FABP elevation higher among patients presenting with hypotension during anesthesia ? ;


Study Design

Observational Model: Case-Only, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT02199275
Study type Observational [Patient Registry]
Source Centre Hospitalier Universitaire de Besancon
Contact
Status Recruiting
Phase N/A
Start date August 2013
Completion date August 2014

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