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NCT01695889 Clinical Trial

Is There a Relationship Between Previous Exposure to General Anesthesia and the Development of Alzheimer´s Disease?

General Anesthesia Clinical Trial

— DEMA  

Official title:
A Case-control Study of Exposure to General Anesthesia and a Diagnosis of Alzheimer´s Disease Later in Life.

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT01695889
Other study ID # DEMA-1
Secondary ID
Status Active, not recruiting
Phase N/A
First received September 27, 2012
Last updated March 24, 2016
Start date May 2012
Est. completion date July 2016

Study information
Verified date March 2016
Source University Hospital, Linkoeping
Contact n/a
Is FDA regulated No
Health authority Sweden: Regional Ethical Review BoardSweden: The National Board of Health and Welfare
Study type Observational

Clinical Trial Summary

The purpose of this study is to compare exposure to general anesthesia between cases with a diagnosis of Alzheimer´s disease and controls without diagnosis, through studies of medical records. The investigators wish to explore if there is a relationship between exposure to general anesthesia and the development of Alzheimer´s disease.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 877
Est. completion date July 2016
Est. primary completion date July 2016
Accepts healthy volunteers No
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Clinical diagnosis of Alzheimer´s disease

- Previous exposure to anesthesia

Exclusion Criteria:

- Inability to retrieve medical records

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

Locations
Country Name City State
Sweden University Hospital Linkoping

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Linkoeping

Country where clinical trial is conducted

Sweden, 

Outcome
Type Measure Description Time frame Safety issue
Primary Exposure to general anesthesia Up to 20 years in retrospect No
Secondary Exposure to inhaled anesthetics Up to 20 years in retrospect No
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