Gastric Residual Volume Clinical Trial
Official title:
The Effect of Carbohydrate Loading on Gastric Residual Volume and Hunger Score: A Single Blind, Randomised Controlled Trial Study
This study conducted is to assess effect of carbohydrate loading (maltodextrin with whey
protein) to gastric volume 2 hours after ingestion via aspiration while doing OGDS (direct
visualisation) and patient's wellbeing (hunger, thirst, weakness, tiredness, anxiety) for all
patient planned for OGDS.
hypothesis H1: There is significant association between carbohydrate loading with residual
gastric volume and subject's wellbeing H0: there is no significant association between
carbohydrate loading with gastric residual volume and subject's wellbeing
Status | Not yet recruiting |
Enrollment | 78 |
Est. completion date | December 2019 |
Est. primary completion date | December 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility |
Inclusion Criteria: - Patient more than 18 years old Exclusion Criteria: - History of upper gastrointestinal surgery - Intestinal obstruction - Patient with vomiting - Mentally disable or who cannot give an informed consent |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
University of Science Malaysia |
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Gustafsson UO, Nygren J, Thorell A, Soop M, Hellström PM, Ljungqvist O, Hagström-Toft E. Pre-operative carbohydrate loading may be used in type 2 diabetes patients. Acta Anaesthesiol Scand. 2008 Aug;52(7):946-51. doi: 10.1111/j.1399-6576.2008.01599.x. Epu — View Citation
Hausel J, Nygren J, Lagerkranser M, Hellström PM, Hammarqvist F, Almström C, Lindh A, Thorell A, Ljungqvist O. A carbohydrate-rich drink reduces preoperative discomfort in elective surgery patients. Anesth Analg. 2001 Nov;93(5):1344-50. — View Citation
Helminen H, Viitanen H, Sajanti J. Effect of preoperative intravenous carbohydrate loading on preoperative discomfort in elective surgery patients. Eur J Anaesthesiol. 2009 Feb;26(2):123-7. doi: 10.1097/EJA.0b013e328319be16. — View Citation
Hofman DL, van Buul VJ, Brouns FJ. Nutrition, Health, and Regulatory Aspects of Digestible Maltodextrins. Crit Rev Food Sci Nutr. 2016 Sep 9;56(12):2091-100. doi: 10.1080/10408398.2014.940415. Review. — View Citation
Kaska M, Grosmanová T, Havel E, Hyspler R, Petrová Z, Brtko M, Bares P, Bares D, Schusterová B, Pyszková L, Tosnerová V, Sluka M. The impact and safety of preoperative oral or intravenous carbohydrate administration versus fasting in colorectal surgery--a — View Citation
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Nygren J, Thorell A, Jacobsson H, Larsson S, Schnell PO, Hylén L, Ljungqvist O. Preoperative gastric emptying. Effects of anxiety and oral carbohydrate administration. Ann Surg. 1995 Dec;222(6):728-34. — View Citation
Tran S, Wolever TM, Errett LE, Ahn H, Mazer CD, Keith M. Preoperative carbohydrate loading in patients undergoing coronary artery bypass or spinal surgery. Anesth Analg. 2013 Aug;117(2):305-13. doi: 10.1213/ANE.0b013e318295e8d1. Epub 2013 Jun 11. — View Citation
* Note: There are 15 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | gastric residual volume | Amount of gastric residual volume (ml) that has been aspirated via OGDS 2 hours after plain water or carbohydrate loading group | 2 hours after plain water or carbohydrate loading | |
Secondary | patient's wellbeing | Subject's wellbeing is assessed via visual analogue scale (VAS) which consist of 5 parameters: hunger, thirst, anxiety, tiredness and weakness. Each scale consisted of ungraded, horizontal lines (with length of 100mm) anchored at two ends. The left end of the scale represented "not at all" which score: 0 and the right end represented and "the most imaginable" which score: 100. Subject need to mark X somewhere along the horizontal line given before drink and before OGDS procedure. Score of each parameter will be reported as mm. | baseline (before drink) and 120minutes after drinking |
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