Gastric Cancer Clinical Trial
Official title:
A Nomogram for Predicting Occult Omental Metastasis in Patients With Gastric Cancer
A complete omentectomy is typically recommended during radical total gastrectomy for gastric cancer, though its impact on survival remains unclear. This study aimed to assess the frequency and risk factors of metastases in the greater omentum in gastric cancer patients undergoing gastrectomy. It will involve a single prospective cohort of consecutive patients who underwent total gastrectomy with complete en bloc omentectomy and modified D2 lymphadenectomy. Post-surgery, the omentum will dissect from the gastrectomy specimen beyond the gastroepiploic vessels and examine separately for pathological assessment. The primary outcome will focus on the detection of omental metastases.
| Status | Recruiting |
| Enrollment | 450 |
| Est. completion date | June 30, 2024 |
| Est. primary completion date | June 30, 2024 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years to 80 Years |
| Eligibility | Inclusion Criteria: 1. pathological confirmation of gastric cancer 2. eligibility for surgical intervention 3. undergoing first rectal cancer surgery 4. acquisition of written informed consent from patients and their families 5. no history of hypertrophic scar or allergic predispositions Exclusion Criteria: 1. absence of postoperative pathology of the omentum 2. diagnosis of multiple primary malignancies 3. intraoperative discovery of widespread implant metastases within the abdominal cavity 4. severe comorbidities |
| Country | Name | City | State |
|---|---|---|---|
| China | Yifan Cheng | Yangzhou | Jiangsu |
| Lead Sponsor | Collaborator |
|---|---|
| Northern Jiangsu People's Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | patients with omental metastases | After the operation, the postoperative pathological examination of the patient indicated the presence of omental metastases | up to 2 weeks after gastric cancer surgery | |
| Primary | patients without omental metastases | After surgery, pathological examination confirmed no omental metastases | up to 2 weeks after gastric cancer surgery |
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