A Web-based Calculator Predicts Heterogeneous Frailty Trajectories

Gastric Cancer Clinical Trial

Official title:

A Web-based Calculator Predicts Heterogeneous Frailty Trajectories Among Elderly Gastric Cancer Survivors

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05982899
• Other study ID #: 2020-273
• Status: Completed
• Start date: March 1, 2021
• Est. completion date: April 1, 2023

Study information

• Verified date: August 2023
• Source: Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To explore the predictive factors of frailty trajectories and develop a web-based nomogram among gastric cancer survivors.

Description:

The aims of this study are to explore the predictive factors of frailty trajectories in gastric cancer patients more comprehensively based on the health ecology theory and to construct a clinically convenient web-based prediction calculator, so as to screen high-risk frailty elderly gastric cancer patients at an early stage in clinical practice, and thus to implement early interventions to improve the prognosis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 412
• Est. completion date: April 1, 2023
• Est. primary completion date: October 1, 2022
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• diagnosed with gastric cancer by endoscopy or pathology;

• age =60 years old;

• radical gastrectomy was proposed;

• be able to communicate simply in writing and verbally.

Exclusion Criteria:

• combined with other sites of malignant tumors;

• combined with severe heart, liver, lung, and renal insufficiency;

• recent using hormones, immunosuppressants;

• with physical disabilities.

Related Conditions & MeSH terms

• Frailty
• Gastric Cancer
• Stomach Neoplasms

Locations

Country	Name	City	State
China	Nanjing medical university	Nanjing
China	Xueyi Miao	Nanjing	Jiangsu

Sponsors (1)

Lead Sponsor	Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	frailty trajectories	Frailty was measured by Tilburg frailty indicator (TFI) scale at discharge, one month, three months, six months and twelve months after surgery.	1 year