The Incidence of Gallstones After Gastric Cancer Surgery

Gastric Cancer Clinical Trial

Official title: The Incidence Risks of Gallstones After Radical Surgery in Different Types of Gastric Cancer

Status Recruiting

Clinical Trial Summary

Through previous clinical observations and literature, we found that the incidence of gallstones in patients after gastric cancer radical resection was significantly higher than that in the normal population (4%). However, its pathogenesis has not been clarified. We compare the risk of gallbladder stones after four different radical gastric cancer surgical methods, in order to provide prevention and treatment strategies for people with gallstones after gastric cancer.

Clinical Trial Description

A large number of clinical studies have found that the incidence of gallstones in patients with radical gastric cancer is higher than that in the normal population. However, its pathogenesis has not been clarified, and there is still controversy about the prophylactic removal of gallbladder in patients with gastric cancer. The investigator's previous study found that there was no statistical difference in the incidence of gallstones after laparoscopic distal gastrectomy (LDG), laparoscopic total gastrectomy (LTG) and laparoscopic proximal gastrectomy (LPG). A common feature of the three surgical methods is that the vagus nerve were more or less cut during the operation. Therefore, we plan to further collect gastric cancer patients undergoing endoscopic submucosal dissection (ESD) surgery in order to answer whether the vagus nerve cut during surgery will increase the incidence of gallstones. ;

Related Conditions & MeSH terms

• Cholecystolithiasis
• Cholelithiasis
• Gallstones
• Gastric Cancer
• Stomach Neoplasms

• NCT number: NCT04250402
• Study type: Observational
• Source: Hepatopancreatobiliary Surgery Institute of Gansu Province
• Contact: Wenbo Meng, M.D., Ph. D.
• Phone: +8613919177177
• Email: mengwb@lzu.edu.cn
• Status: Recruiting
• Start date: February 14, 2020
• Completion date: December 30, 2023