Gastric Cancer Clinical Trial
Official title:
The Impact of Postoperative Enteral Immunonutrition on Postoperative Complications and Survival in Gastric Cancer Patients
Immunomodulating enteral nutrition in the perioperative period may reduce postoperative
complications in cancer patients. Little is known if this effect translates to the better
survival.
The aim of study was to assess the impact of postoperative immunomodulating enteral nutrition
on postoperative complications and survival of gastric cancer patients.
The group of 98 gastric cancer patients were randomly assigned for postoperative
immunomodulating enteral nutrition n=44 (Reconvan ,Fresenius Kabi), or standard enteral
nutrition n=54 (Peptisorb, Nutricia). Postoperative complications, mortality, 6-month, 1-year
and 5-year survival were analyzed.
Treatment of gastric cancer often requires major surgery and carries the risk of
postoperative complications and fatal outcomes. Mortality rates after gastrectomy due to
gastric cancer have been reported as 2-5%, while the incidence of postoperative complications
was 10 to over 40%.
Immunomodulating enteral nutrition in the perioperative period may reduce postoperative
complications in cancer patients. Little is known if this effect translates to the better
survival.
The aim of study was to assess the impact of postoperative immunomodulating enteral nutrition
on postoperative complications and survival of gastric cancer patients.
The group of 98 gastric cancer patients were randomly assigned for postoperative
immunomodulating enteral nutrition n=44 or standard enteral nutrition n=54. Following the
initial randomization, the patients received either standard nutrition (oligopeptide,
low-fat, isocaloric, non-residue diet - Peptisorb, Nutricia) or immunomodulating nutrition
(protein rich, isocaloric, no-residue diet including arginine, glutamines and omega-3 fatty
acids - Reconvan, Fresenius Kabi). Postoperative complications, mortality, 6-month, 1-year
and 5-year survival were analyzed.
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