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Clinical Trial Summary

A single-arm, open-label early-stage exploratory clinical study to evaluate the safety, tolerability and efficacy of Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in subjects with gastric/gastroesophageal junction adenocarcinoma.


Clinical Trial Description

This study is an open-label, single-/multiple-dose infusion, adaptive dose-escalation designed early exploratory clinical trial aiming to evaluate the safety, tolerability, and efficacy of Claudin18.2-Targeted Chimeric Antigen Receptor T Cell Injection in subjects with CLDN18.2 positive and pathologically confirmed locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06353152
Study type Interventional
Source Peking University
Contact Lin Shen, PHD
Phone +86 1088196561
Email linshenpku@163.com
Status Recruiting
Phase Phase 1
Start date November 17, 2023
Completion date November 16, 2025

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