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TAS-102 and Irinotecan in 2L+ Gastric and Gastroesophageal Adenocarcinoma

Gastric Adenocarcinoma Clinical Trial

Official title:
A Phase Ib Multicenter Study of TAS-102 in Combination With Irinotecan in Patients With Advanced Recurrent or Unresectable Gastric and Gastroesophageal Adenocarcinoma After at Least One Line of Treatment With a Fluoropyrimidine and Platinum Containing Regimen

Clinical Trial Summary

This is a phase Ib single-arm, open-label clinical trial determining the feasibility and efficacy of TAS-102 and irinotecan in subjects with advanced gastric and gastroesophageal adenocarcinoma. These are subjects who are not candidates for curative treatments and who have received at least one prior line of chemotherapy with a fluoropyrimidine and platinum agent.

Clinical Trial Description

Treatment on study will be administered in 14 day cycles. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04074343
Study type Interventional
Source University of California, Irvine
Contact
Status Completed
Phase Phase 1
Start date August 26, 2019
Completion date July 21, 2022
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