Gambling Disorder Clinical Trial
Official title:
The Effect of Transcranial Direct Current Stimulation on Decision Making and Cognitive Flexibility in Gambling Disorder
The investigators conducted a double-blind randomised sham-controlled study. Upon enrollment
into the study, participants were randomly assigned to one of two conditions: (i) active
group: anodal stimulation over the right dlPFC (n = 10) or (ii) sham stimulation group (n =
10). Participants and raters were blinded to the condition.
Subsequently, the participants were administered the IGT and the Wisconsin Card Sorting Test
by a trained neuropsychologist in a quiet laboratory. A computerized version of standard IGT
was used. The order of the tasks performed in a single session was randomised.
After the psychiatric and neurocognitive assessment, participants received three sessions of
20-minute active or sham anodal tDCS (once a day, every other day).
Wisconsin Card Sorting Test and a modified version of Iowa Gambling Test were readministered
after the last application. The order of the tasks was randomized again. A brief
questionnaire on study blinding was also administered. Safety was assessed through open-ended
questions based on the tDCS adverse events questionnaire
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