Clinical Trials Logo

Clinical Trial Summary

The prevalence of neurodegenerative diseases will increase over the next decades driven by ageing population. It seems important to develop reliable, replicable and accessible diagnostic tools.

This is a prospective study whose objective is to study the spatio-temporal parameters of gait in patients with Alzheimer's and Lewy body diseases. 64 patients were included in this study. A comparison of the two pathologies was conducted, followed by an analysis based on four groups (mild, severe Alzheimer's disease, mild, severe Lewy body disease) and a study of the severity of the diseases. To study these parameters, we used the Gaitrite treadmill.

The analysis of spatio-temporal parameters of walking in Alzheimer's disease and Lewy body disease enables to identify discriminating variables between the two pathologies. The probability of suffering from an Alzheimer's disease decreases with the pace increase but increases with variations in length of the step, and with the rotation of the foot. While the probability of suffering from Lewy body disease increases with the pace, variations in the step duration, and the duration of double support.

These results are interesting but do not allow to establish a diagnostic score for these two diseases. The monitoring of the variations of these parameters at individual level would probably be more relevant and would enable to detect dual pathologies.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03399591
Study type Observational
Source University Hospital, Strasbourg, France
Contact Jérémie PERISSE, MD
Phone 33 3 88 11 55 11
Email jeremie.perisse@chru-strasbourg.fr
Status Recruiting
Phase
Start date May 2, 2017
Completion date March 2019

See also
  Status Clinical Trial Phase
Completed NCT03593512 - Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy N/A
Completed NCT04117737 - A Pilot Study of Virtual Reality and Antigravity Treadmill for Gait Improvement in Parkinson N/A
Recruiting NCT04265482 - Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly
Completed NCT03192046 - Bracing for Walking in Parkinson's Disease N/A
Terminated NCT01678547 - Robot Walking Rehabilitation in Stroke Patients N/A
Recruiting NCT05510739 - Support for Physical Activity in Everyday Life With Parkinson's Disease N/A
Recruiting NCT05417399 - Influence of Hawthorne Effect and Dual-tasks on Gait in CP
Completed NCT05683925 - Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Characteristics in Parkinson's Disease N/A
Recruiting NCT05110053 - Spinal Cord sTimulation thEraPy for Parkinson's Disease Patients With Gait Problems Phase 1
Recruiting NCT05801874 - Gait and Posture Analysis in Hemiparetic Patients Through Optoelectronic Systems, "Smart" Tools and Clinical Evaluation
Recruiting NCT04137146 - SNS for Treatment of PD Gait Disorder N/A
Terminated NCT05622786 - Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients N/A
Recruiting NCT04855825 - Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS N/A
Recruiting NCT05022147 - Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease Phase 1
Completed NCT04266743 - FeetMe® Monitor: Alternative for the Evaluation of Gait Speed After Stroke N/A
Completed NCT04622657 - Validity Reliability of The Dubousset Functional Test in Parkinson Disease N/A
Completed NCT02356536 - The Effect of a Wearable Cueing Device on Freezing of Gait in Parkinson's Disease Phase 1
Completed NCT01108029 - Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease Phase 4
Completed NCT00914095 - Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease (PARKGAIT-II) Phase 4
Completed NCT03314610 - Effect of Need to Void on Parkinsonian Gait