Furcation Defects Clinical Trial
Official title:
Evaluation of Adjunctive Effect of 1% Metformin To Platelet Rich Fibrin For Mandibular Class II Furcation Defects: A Randomized Controlled Clinical Trial
Verified date | July 2017 |
Source | Government Dental College and Research Institute, Bangalore |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The aim of the present trial is to evaluate the efficacy of PRF with 1% MF in treatment of mandibular class II furcation defects and its comparison to PRF and access therapy alone.
Status | Completed |
Enrollment | 75 |
Est. completion date | May 2016 |
Est. primary completion date | May 2016 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 30 Years to 50 Years |
Eligibility |
Inclusion Criteria: - Buccal degree II furcation defects in endodontically vital, asymptomatic mandibular first and second molars with a radiolucency in the furcation area on an intraoral periapical radiograph with probing depth (PD) = 5mm and horizontal = PD 3mm after phase I therapy i.e, scaling and root planing (SRP); - No history of antibiotic or periodontal therapy in the preceding 6 months. Exclusion Criteria: Aggressive periodontitis patients - Systemic conditions known to affect the periodontal status; - Medications known to affect the outcomes of periodontal therapy; - Hematological disorders and insufficient platelet count (<100,000/mm3); - Pregnancy/lactation; - Smoking and tobacco use in any form - Immunocompromised individuals; - Those having unacceptable oral hygiene (plaque index [PI] >1.5). - Teeth with furcation involvement, non-vital teeth, and carious teeth indicated for restorations and mobility of at least grade II were also excluded. |
Country | Name | City | State |
---|---|---|---|
India | Government Dental College and Research Institute | Bangalore | Karnataka |
Lead Sponsor | Collaborator |
---|---|
Government Dental College and Research Institute, Bangalore |
India,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Radiographic bone fill assessed in percentage | assessed in percentage | baseline to 9 months | |
Secondary | probing depth measured in mm | measured in mm | baseline to 9 months | |
Secondary | Relative vertical attachment level measured in mm | measured in mm | baseline to 9 months | |
Secondary | Relative horizontal attachment level measured in mm | measured in mm | baseline to 9 months | |
Secondary | modified sulcus bleeding index | 0-3 scale | baseline to 9 months | |
Secondary | plaque index | 0-3 scale | baseline to 9 months |
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT04851548 -
Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation Involvement
|
N/A | |
Recruiting |
NCT06025955 -
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
|
N/A | |
Not yet recruiting |
NCT05721313 -
Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study
|
N/A | |
Not yet recruiting |
NCT05481580 -
Restorations and Furcation Involvement on Molars
|
||
Recruiting |
NCT06060340 -
Clinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case Series
|
Early Phase 1 | |
Recruiting |
NCT05541614 -
Flapless Application of Enamel Matrix Derivative in Class II Mandibular Furcation Defects
|
N/A | |
Terminated |
NCT04059458 -
Mandibular Furcation III Regeneration (FURC-III-REGEN)
|
Phase 4 | |
Withdrawn |
NCT04017429 -
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)
|
N/A | |
Terminated |
NCT04059445 -
Mandibular Furcation II Regeneration
|
Phase 4 | |
Withdrawn |
NCT03917030 -
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation Defects
|
N/A | |
Completed |
NCT02369250 -
Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation Defects
|
Phase 4 | |
Not yet recruiting |
NCT06116487 -
MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars
|
||
Completed |
NCT03578744 -
Comparison of Platelet Rich Fibrin as Graft & Membrane Vs Hyaluronic Acid & Amniotic Membrane in the Treatment of Interradicular Defects
|
N/A | |
Recruiting |
NCT03180658 -
Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
|
N/A | |
Active, not recruiting |
NCT05259982 -
Vital Root-resective Therapy in Furcation-involved Maxillary Molars
|
N/A | |
Active, not recruiting |
NCT02132806 -
Piezosurgery in the Treatment of Class II Furcation Involvement
|
N/A | |
Completed |
NCT02102360 -
Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.
|
Phase 4 | |
Not yet recruiting |
NCT06270303 -
Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects
|
N/A | |
Completed |
NCT03354182 -
Surgical Treatment of Mandibular Furcations Using a Xenograft With/Without a Collagen Membrane
|
N/A | |
Completed |
NCT04842188 -
Furcation Treatment With L-PRF and aPDT
|
N/A |