Low Fructose Diet in Diabetes Type 2

Fructose Metabolism Disorder Clinical Trial

Official title:

Effects of Low Fructose Diet on Glycemic Control in Patients With Type 2 Diabetes

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03352596
• Other study ID #: 93567
• Status: Active, not recruiting
• Phase: N/A
• First received: November 13, 2017
• Last updated: November 20, 2017
• Start date: January 1, 2017
• Est. completion date: November 30, 2017

Study information

• Verified date: August 2017
• Source: National Nutrition and Food Technology Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran. Suitable treatments for type 2 diabetes include changing lifestyle with exercise, nutrition, and drug use. New research suggests that added sugar, especially fructose, is the main trigger for diabetes and pre-diabetes even more potent than other carbohydrates. Fructose has a low glycemic index (23μg =) and slowly increases blood glucose levels. Therefore, it is thought that replacing fructose instead of glucose can have a positive effect on glycemic control of diabetic patients..

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 48
• Est. completion date: November 30, 2017
• Est. primary completion date: October 1, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 70 Years

Eligibility

Inclusion Criteria:

1. Age of 70-40 years

2. body mass index(BMI) between 18.5 and 27

3. Type 2 diabetes People who only control their diabetes by using glucose lowering tablets Type 2 diabetes (1 to 10 years)

Exclusion Criteria:

1. Pregnancy and lactation

2. Thyroid gland disorders

3. Kidney disease and inflammation

4. Follow the weight loss regimen 6 months before starting the study

5. Usage of fatty and fatty foods, fiber powder Vitamin A Mineral Supplements, Omega 3

6. Taking glucocorticoid drugs and non-steroidal anti-inflammatory drugs

Related Conditions & MeSH terms

• Fructose Intolerance
• Fructose Metabolism Disorder
• Metabolic Diseases

Intervention

Other:
• low frutose diet

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
National Nutrition and Food Technology Institute

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	fasting blood suger(FBS)		8 weeks
Primary	Homeostatic model assessment and insulin resistance(HOMA-IR)		8weeks
Primary	insulin		8 weeks
Secondary	Triglyceride		8 weeks
Secondary	Total cholestrole		8 weeks
Secondary	LDL-C		8 weeks
Secondary	HDL-C		8 weeks
Secondary	Blood pressure		8 weeks