Frailty Clinical Trial
Official title:
Frailty Screening in the Swedish Emergency Department Setting
Verified date | June 2022 |
Source | University Hospital, Linkoeping |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This prospective observational study will investigate the correlation of frailty in relation to serious outcomes. Serious outcomes are defined as: mortality within 30 days, admission to hospital, length of stay in the Emergency Department(ED), in hospital length of stay and revisits to the ED. The exposure, frailty, will be assessed according to Clinical Frailty Scale. ED patients >65 years of age in a Swedish regional health care system (Region Östergötland, Sweden) comprising three EDs in Linköping, Norrköping and Motala. The outcomes will be compared according to the degree of frailty and censored over 7, 30 and 90 days respectively.
Status | Completed |
Enrollment | 1800 |
Est. completion date | November 14, 2021 |
Est. primary completion date | November 14, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 65 Years and older |
Eligibility | Inclusion Criteria: - =65 years, able to answer any questions, alternatively have a proxy Exclusion Criteria: - Patients: <65 years |
Country | Name | City | State |
---|---|---|---|
Sweden | University Hospital Linköping | Linköping | Östergötland |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Linkoeping |
Sweden,
Kaeppeli T, Rueegg M, Dreher-Hummel T, Brabrand M, Kabell-Nissen S, Carpenter CR, Bingisser R, Nickel CH. Validation of the Clinical Frailty Scale for Prediction of Thirty-Day Mortality in the Emergency Department. Ann Emerg Med. 2020 Sep;76(3):291-300. doi: 10.1016/j.annemergmed.2020.03.028. Epub 2020 Apr 24. — View Citation
Rockwood K, Song X, MacKnight C, Bergman H, Hogan DB, McDowell I, Mitnitski A. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489-95. — View Citation
Rockwood K, Theou O. Using the Clinical Frailty Scale in Allocating Scarce Health Care Resources. Can Geriatr J. 2020 Sep 1;23(3):210-215. doi: 10.5770/cgj.23.463. eCollection 2020 Sep. — View Citation
Wallis SJ, Wall J, Biram RW, Romero-Ortuno R. Association of the clinical frailty scale with hospital outcomes. QJM. 2015 Dec;108(12):943-9. doi: 10.1093/qjmed/hcv066. Epub 2015 Mar 15. — View Citation
Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med. 2011 Feb;27(1):1-15. doi: 10.1016/j.cger.2010.08.009. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mortality in 30 days | Investigate level of mortality in cohort at 30 days | All cause mortality up to 90 days from index visit | |
Secondary | Mortality in 7 and 90 days | Investigate level of mortality in cohort at 7 and 90 days | All cause mortality up to 90 days from index visit | |
Secondary | Admission to hospital | Investigate level of all cause admissions in cohort | Hospital admission on index visit, censored at 90 days | |
Secondary | ED length of stay | Investigate length of stay at ED | Length of stay at ED, censored at 4 days | |
Secondary | Hospital length of stay | Investigate hospital length of stay | Hospital length of stay from index visit, censored at 90 days | |
Secondary | Revisitis to the ED | Number of newly registered visits to the emergency department after index visit | Number of newly registered visits to the emergency department after index visit, censored at 90 days | |
Secondary | Fall prevalence after the index visit | Falls that resulted in further ED visits | Falls that resulted in further ED visits after index visit, censored in 90 days | |
Secondary | Alterations in medication during the visit (based on codes for Anatomical, Therapeutic, Chemical classification (ATC-code)) | Alterations in medication and during the follow-up period | Alterations in medications from index visit and during the follow-up period, censored at 90 days |
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