Clinical Trials Logo

Clinical Trial Summary

It is hypothesized that the negative pressure associated with an IVAC is not sufficient to remove BMP-2 from a surgical wound.

BMP-2 is commonly used in open tibia fractures at the time of definitive wound closure, and these wounds are prone to increased swelling and wound complications. The recent observation that IVAC decreases wound edema and increases oxygenation has led to their use in such cases. Used in conjunction, it is entirely possible that the negative pressure exerted by the IVAC can remove BMP-2 from surgical site and therefore decreases the effectiveness of BMP-2. We seek to determine if BMP-2 is present in effluent from the IVAC. If in this study the hypothesis is found to be wrong, and BMP-2 is found within the IVAC effluent, we are prepared to proceed with a follow-up study to quantify the BMP-2 removed by the IVAC.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00829621
Study type Interventional
Source University of Missouri-Columbia
Contact
Status Completed
Phase N/A
Start date December 2008
Completion date December 2013

See also
  Status Clinical Trial Phase
Terminated NCT03781817 - Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures Phase 4
Recruiting NCT03796572 - Regional Blocks for Lateral Condyle Fractures Phase 4
Recruiting NCT02957240 - Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures N/A
Terminated NCT03196258 - Cognitive Behavioural Therapy to Reduce Persistent Post-Surgical Pain After Fracture N/A
Terminated NCT05655130 - Distal Radius Steroid Phase 1
Not yet recruiting NCT06400732 - Post Market Evaluation of Clinical Safety and Performance of the Fitbone Transport and Lengthening System
Terminated NCT00610701 - Lateral Versus Anterior Spanning External Fixator for Tibial Plateau Fractures N/A
Completed NCT03991546 - Pain and Narcotic Usage After Orthopaedic Surgery N/A
Completed NCT00843973 - Osteogenic Cell Viability in Bone Graft N/A
Recruiting NCT04730739 - FastFrame Knee Spanning and Damage Control Kit PMCF N/A
Completed NCT03525821 - Intranasal Ketamine and Fracture Reduction in Pediatric Emergencies (KETAPED) Phase 3
Completed NCT04026074 - Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations. Phase 4
Withdrawn NCT01812863 - Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair N/A
Terminated NCT03673358 - Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Pilot N/A
Recruiting NCT04274530 - Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial N/A
Completed NCT00610987 - Antibiotic Prophylaxis in Orthopaedic Traumatology N/A
Recruiting NCT06130397 - AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
Completed NCT03298425 - The Use of NMES With Pelvic Fracture Rehabilitation N/A
Completed NCT02390856 - Volar Plate vs. Conventus DRS Fixation N/A
Recruiting NCT05260463 - LOQTEQ® Antibacterial Pre-Market Study N/A