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Basophile Activation Testing (BAT) in Hazelnut Allergy (Hazelnut BAT Study)

Food Allergy Clinical Trial

Official title:
Correlation of the in Vivo Food Provocation Test With the in Vitro Basophile Activation Test in Hazelnut Allergic Patients

Clinical Trial Summary

The proposed study intends to compare the outcome of food challenge in hazelnut allergic patients with the outcome of basophile activation tests using hazelnut extract and components.

Clinical Trial Description

Accurate diagnosis of food allergy depends on food challenge outcome. The proposed study intends to compare the outcome of food challenge in hazelnut allergic patients with the outcome of basophile activation tests using hazelnut extract and components to evaluate the diagnostic utility of basophile activation testing. With a view towards improved in vitro diagnostic methods, the investigators intend to evaluate the diagnostic potential of basophile activation testing in patients with hazelnut allergy confirmed by a positive provocation or supported by a convincing history of anaphylactic reaction(s) to hazelnut in the past, patients with pollinosis but no symptoms of hazelnut allergy and non-atopic control subjects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03079206
Study type Interventional
Source University of Zurich
Contact
Status Completed
Phase N/A
Start date February 22, 2017
Completion date November 10, 2020
View Details
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