Food Allergy Proved Clinical Trial
Official title:
Association Between Asthma and Food Allergy in Children and Adults
Prevalences of food allergies and asthma increased in the population during the last decades.
These two pathologies, responsible for a real burden, are often associated and are to be
considered as comorbidities; this aspect is more and more studied in the literature and many
authors tried to find a link between diets and asthma. The narrow link between these two
atopic pathologies and the fact that food allergy can come along with respiratory symptoms
also in patients without history of asthma must be better understood, considered into the
management of food allergy. The main objective of this study is to study the prevalence of
signs and/or symptoms suggestive of bronchial hyperreactivity, during an oral food challenge
(OFC) in patients older than 5 years. The secondary objective is to study the risk factors to
develop asthma during a food allergy reaction.
This historical-prospective single center study , was realized in the Allergy Unit of the
University Hospital of Montpellier. All the patients having been hospitalized for a positive
OFC between January, 2001 and January, 2016 were included. The diagnosis of asthma was
established according to the recommended international clinical and physiological criteria.
Prevalence of bronchial hyperreactivity during OFC among those with positive OFC, was
calculated. The search for risk factors was made by a logistic regression univariate then
multivariate, completed by a decision tree.
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