Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT01219439 |
| Other study ID # |
RMA-00-14 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
July 2007 |
| Est. completion date |
December 2022 |
Study information
| Verified date |
May 2023 |
| Source |
Reproductive Medicine Associates of New Jersey |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
The researchers propose to investigate the causes, incidence, and time-related events of
chromosomal and physiologic abnormalities as they relate to patient diagnosis, fertility
drugs utilized, and in vitro laboratory culture conditions.
Description:
We propose to identify a group of parameters that have significant predictive value for
assisted reproductive technology outcomes. We seek to test, standardize and implement better
methods for the freezing of oocytes and sperm prior to these techniques being used in the
clinical setting. We seek to develop new methods to optimize the determination of genes and
chromosomes in gametes. We hope to develop new cell surgery or micromanipulation techniques
(e.g. use of cell drills and lasers in order to enhance the efficiency of procedures such as
ICSI, assisted hatching, biopsy) as well as other manipulations. We will test the safety and
efficiency of micro fluidics and automation in the Embryology lab. This has the potential to
reduce cost, human errors, temperature and physical changes. We hope to develop new methods
and media and media supplements normally found in the reproductive tract that allow for
higher survival of gametes in vitro. We will also test the proficiency of laboratory staff
members on techniques and/or procedures performed in the in-vitro fertilization laboratory.
We will perform Quality Control to review how changes in temperature and setting can effect
specimens
