Effect of Duration and Follicle Diameter During Oocyte Pick up on Embryological Parameters

Follicle Size Clinical Trial

Official title:

Does Follicle Diameter and Total Duration Spent for Oocyte Pick up Has Any Effect on Embryological Parameters and Clinical Pregnancy Rates

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05666401
• Other study ID #: Eurofertil-OPU
• Status: Completed
• Start date: March 19, 2022
• Est. completion date: February 17, 2024

Study information

• Verified date: February 2024
• Source: Eurofertil IVF Health Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Investigators aim to investigate if the time spent for smaller follicles worth to deal with. The difference between follicle groups are recorded for embryological parameters. Results will be analysed for yielding transfer embryo and pregnancy rates between groups.

Description:

There are papers about follicle dimensions and volumes studying their effect on embryologic parameters. But most of these studies are far from practical approach and are not easily applicable, such as 3D volumetric measurement is not feasible for most of the clinics. Also one of the points important for us it to evaluate the duration of the procedure and the possible positive effect of shortening the duration for better results. Investigators plan to measure the follicles just before puncture and arrange two groups. Group 1,follicles with diameter of 17 mm and more, and group 2 follicles between14-17 mm. Maturation, fertilization, cleavage characteristics are recorded. The source of chosen transfer embryo and crio-preserved embryos per cycle is also point of interest.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 291
• Est. completion date: February 17, 2024
• Est. primary completion date: February 17, 2024
• Gender: Female
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• 20-40 year old women

Exclusion Criteria:

• History of recurrent implantation failure (RIF)

• Known chromosomal abnormality

• Severe male factor and azospermia

Related Conditions & MeSH terms

• Follicle Size

Intervention

Procedure:
• follicle diameter and duration of procedure
to investigate if smaller follicles thrive embryos as the bigger follicles

Locations

Country	Name	City	State
Turkey	Bursa Eurofertil IVF center	Bursa
Turkey	Eurofertil IVF center	Bursa

Sponsors (1)

Lead Sponsor	Collaborator
Eurofertil IVF Health Center

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	transfer embryo	comparing groups as the source of transfer embryo	5 to 7 days
Secondary	clinical pregnancy	comparing groups as the source of implanted embryo	3 weeks